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Einfluß der Umwelt auf das Abwehrsystem der menschlichen Haut

  • Conference paper
Fortschritte der praktischen Dermatologie und Venerologie

Part of the book series: Fortschritte der praktischen Dermatologie und Venerologie ((DERMATOLOGIE,volume 14))

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Zusammenfassung

Die Haut als Grenzorgan des Organismus gegenüber der Umwelt stellt nicht nur eine einfache mechani sche und thermoregulatorische Barriere dar, son dern ist auch ein hochentwickeltes Immunorgan. Da Umwelteinflüsse primär die Epidermis betreffen, kommt dem Immunsystem der Epidermis eine be sondere Bedeutung zu. Wir wissen heute, daß die Epidermis ein vollständiges Immunorgan darstellt, welches die wesentlichen Komponenten zur Initiie rung einer Immunantwort enthält. Demnach befin den sich in normaler Epidermis antigenpräsentierende dendritische Zellen und Lymphozyten [22]. Darüber hinaus sind die meisten Zellen der Epider mis mit der Fähigkeit ausgestattet, Zytokine zu pro duzieren [19]. Die Funktion des epidermalen Im munsystems kann durch Umweltfaktoren chemi scher, physikalischer und biologischer Natur sowie durch Mikroben nachhaltig beeinflußt werden. Im Hinblick auf die Zunahme von Überempfindlich keitsreaktionen und Lichtdermatosen ist der Einfluß von toxischen bzw. allergischen Noxen sowie von UV-Licht von besonderer Bedeutung.

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Authors
  1. Thomas A. Luger
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  2. Thomas Schwarz
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Editors and Affiliations

  1. Dermatologische Klinik und Poliklinik, der Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, D-80337, München, Deutschland

    Gerd Plewig  & Hans Christian Korting  & 

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© 1995 Springer-Verlag Berlin Heidelberg

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Luger, T.A., Schwarz, T. (1995). Einfluß der Umwelt auf das Abwehrsystem der menschlichen Haut. In: Plewig, G., Korting, H.C. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79156-7_1

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  • DOI: https://doi.org/10.1007/978-3-642-79156-7_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79157-4

  • Online ISBN: 978-3-642-79156-7

  • eBook Packages: Springer Book Archive

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