Guillain-Barré Syndrome in the 1990’s

  • D. Hunt
  • J. Lang
  • D. J. Cook
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1995)


Guillain-Barré syndrome is the most common acute polyradiculopathy. While generally a benign, spontaneously resolving condition, its course may be complicated by ventilatory failure and arrhythmias, and about 10 to 15% of patients are left with severe neurological deficits.


Plasma Exchange Immune Globulin Cranial Nerve Involvement Acute Intermittent Porphyria Antecedent Event 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Parry JP (ed) (1993) Guillain-Barré syndrome. Thieme Medical Publishers, Inc. New YorkGoogle Scholar
  2. 2.
    Mobley WC, Wolinsky JS (1982) Scientific overview of inflammatory demyelinating polyneuropathy and design of the North American Colloborative Study of Plasma Exchange in Guillain-Barré Syndrome. Prog Clin Biol Res 106: 159–187PubMedGoogle Scholar
  3. 3.
    Alter M (1990) The Epidemiology of Guillain-Barré Syndrome. Ann Neurol 27 (Suppl): S7–S12PubMedCrossRefGoogle Scholar
  4. 4.
    McKhann GM, Griffin JW, Cornblath DR, et al and the Guillain-Barré Syndrome Study Group (1988) Plasmapheresis and Guillain-Barré Syndrome: Analysis of prognostic factors and the effect of plasmapheresis. Ann Neurol 23: 347–353PubMedCrossRefGoogle Scholar
  5. 5.
    Ashbury AK, Arnason BG, Karp HR, McFarlin DE (1978) Criteria for diagnosis of Guillain-Barré syndrome. Ann Neurol 3: 565CrossRefGoogle Scholar
  6. 6.
    Lang JD, Cook DJC, Hunt DL (1994) Plasma exchange for Guillain-Barré Syndrome: A systematic overview. J Gen Int Med 9 (Supp 2): 32Google Scholar
  7. 7.
    Guillain-Barré Syndrome Study Group (1985) Plasmapheresis and acute Guillain-Barré syndrome. Neurology 35: 1096–1104Google Scholar
  8. 8.
    French Cooperative Group on Plasma Exchange in Guillaine-Barré Syndrome (1987) Efficiency of plasma exchange in Guillain-Barré Syndrome: Role of replacement fluids. Ann Neurol 22: 753–761CrossRefGoogle Scholar
  9. 9.
    French Cooperative Group on Plasma Exchange in Guillaine-Barré Syndrome (1992) Plasma exchange in Guillain-Barré Syndrome: One year follow-up. Ann Neurol 32: 94–97CrossRefGoogle Scholar
  10. 10.
    Farkkila M, Kinnunen E, Haapanen E, Iivanainem M (1987) Guillain-Barré syndrome: Quantitative measurement of plasma exchange therapy. Neurology 37: 837–840PubMedGoogle Scholar
  11. 11.
    Osterman PO, Fagius J, Lundemo G, et al (1984) Beneficial effects of plasma exchange in acute inflammatory polyradiculoneuropathy. Lancet 2: 1296–1298PubMedCrossRefGoogle Scholar
  12. 12.
    Greenwood RJ, Newson-Davis J, Hughes RAC, et al (1984) Controlled trial of plasma exchange in acute inflammatory polyradiculoneuropathy. Lancet 1: 877–879PubMedCrossRefGoogle Scholar
  13. 13.
    van der Meche FGA, Schmitz PIM, and the Dutch Guillain-Barré Study Group (1992) A randomized trial comparing immune globulin and plasma exchange in Guillain-Barré Syndrome. N Engl J Med 326: 1123–1129PubMedCrossRefGoogle Scholar
  14. 14.
    Hughes RAC, Newsom-Davis JM, Perkin GD, Pierce JM (1978) Controlled trial of prednisolone in acute polyneuropathy. Lancet 2: 750–753PubMedCrossRefGoogle Scholar
  15. 15.
    Guillain-Barré Syndrome Steroid Trial Group (1993) Double-blind trial of intravenous methylprednisolone in Guillain-Barré Syndrome. Lancet 341: 586–590Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • D. Hunt
  • J. Lang
  • D. J. Cook

There are no affiliations available

Personalised recommendations