Skip to main content

Left Ventricular Function in COPD

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1995))

  • 154 Accesses

Abstract

The relationships between chronic obstructive pulmonary disease (COPD) and left ventricular (LV) dysfunction have been the subject of debate for several decades. Improved techniques to assess LV function have recently clarified this subject [1]. In the absence of an associated cause of left cardiopathy, the left ventricle of a COPD patient must be considered as normal [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wise RA (1991) COPD and the peripheral circulation. In: Cherniak NS (ed) Chronic obstructive pulmonary disease. WB Saunders, Philadelphia, pp 167–177

    Google Scholar 

  2. Aldrich TK, Hendler JM, Vizioli LD, Park M, Multz AS, Shapiro SM (1993) Intrinsic positive end-expiratory pressure in ambulatory patients with airways obstruction. Am Rev Respir Dis 147: 845–849

    PubMed  CAS  Google Scholar 

  3. Fleury B, Murciano D, Talamo C, Aubier M, Pariente R, Milic-Emili J (1985) Work of breathing in patients with chronic obstructive pulmonary disease in acute respiratory failure. Am Rev Respir Dis 131: 822–827

    PubMed  CAS  Google Scholar 

  4. Decramer M, DeTroyer A, Kelly S, Zocchi L, Macklem PT (1984) Regional differences in abdominal pressure swings in dogs. J Appl Physiol 57: 1682–1687

    PubMed  CAS  Google Scholar 

  5. Takata M, Robotham JL (1992) Effects of inspiratory diaphragmatic descent on inferior vena caval venous return. J Appl Physiol 72: 597–607

    PubMed  CAS  Google Scholar 

  6. Murciano D, Aubier M, Bussi S, Derenne JP, Pariente R, Milic-Emili J (1982) Comparison of esophageal, tracheal and mouth occlusion pressure in patients with chronic obstructive pulmonary disease during acute respiratory failure. Am Rev Respir Dis 126: 837–841

    PubMed  CAS  Google Scholar 

  7. Derenne JP, Fleury B, Pariente R (1988) Acute respiratory failure of chronic obstructive pulmonary disease. Am Rev Respir Dis 138: 1006–1033

    Article  PubMed  CAS  Google Scholar 

  8. Degaute OP, Domenigretti J, Naeije R, Vincent JL, Treyvaud D, Perret C (1981) Oxygen delivery in acute exacerbation of chronic obstructive pulmonary disease. Effects of controlled oxygen therapy. Am Rev Respir Dis 124: 26–30

    PubMed  CAS  Google Scholar 

  9. Aubier M, Murciano D, Milic-Emili J (1980) Effects of the administration of O2 on ventilation and blood gases, in patients with chronic obstructive pulmonary disease during acute respiratory failure. Am Rev Respir Dis 122: 747–754

    PubMed  CAS  Google Scholar 

  10. Marthan R, Castaing Y, Manier G, Guenard H (1985) Gas exchange alteration in patients with chronic obstructive lung disease. Chest 87: 470–475

    Article  PubMed  CAS  Google Scholar 

  11. Field S, Kelly SM, Macklem PT (1982) The oxygen cost of breathing in patients with cardiorespiratory disease. Am Rev Respir Dis 126: 9–13

    PubMed  CAS  Google Scholar 

  12. Scharf SM, Graver M, Khilnani S, Balaban K (1992) Respiratory phasic effects of inspiratory loading on left ventricular hemodynamics in vagotomized dogs. J Appl Physiol 73: 995–1003

    PubMed  CAS  Google Scholar 

  13. Scharf SM, Bianco JA, Tow DE, Brown R (1981) The effects of large negative intrathoracic pressure on left ventricular function in patients with coronary artery disease. Circulation 63: 871–876

    Article  PubMed  CAS  Google Scholar 

  14. Scharf SM, Woods BOB, Brown R, Parisi AF, Miller MJ, Tow DE (1987) Effects of the Mueller maneuver on global and regional left ventricular function in angina pectoris with or without previous myocardial infarction. Am J Cardiol 59: 1305–1309

    Article  PubMed  CAS  Google Scholar 

  15. Janicki JS, Weber KT (1980) The pericardium and ventricular interaction, distensibility and function. Am J Physiol 238: H494–H503

    PubMed  CAS  Google Scholar 

  16. Weber KT, Janicki JS, Shroff S, Fishman AP (1981) Contractile mechanics and interaction of the right and left ventricles. Am J Cardiol 47: 686–695

    Article  PubMed  CAS  Google Scholar 

  17. Guyton AC, Adkins LH (1954) Quantitative aspects of the collapse factor in relation to venous return. Am J Physiol 177: 523–527

    PubMed  CAS  Google Scholar 

  18. Lloyd TC Jr (1983) Effect of inspiration on inferior vena cava blood flow in dogs. J Appl Physiol 55: 1701–1708

    PubMed  Google Scholar 

  19. Takata M, Wise RA, Robotham JL (1990) Effects of abdominal pressure on venous return: Abdominal vascular zone conditions. J Appl Physiol 69: 1961–1972

    PubMed  CAS  Google Scholar 

  20. Nakhjavan FK, Palmer WH, McGregor M (1966) Influence of respiration on venous return in pulmonary emphysema. Circulation 33: 8–16

    PubMed  CAS  Google Scholar 

  21. Brookhard JM, Boyd TF (1947) Local differences in intrathoracic pressure and their relation to cardiac filling pressure in the dog. Am J Physiol 148: 434–444

    Google Scholar 

  22. Walley KR, Lewis TH, Wood LDH (1990) Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs. Circ Res 67: 628–635

    PubMed  CAS  Google Scholar 

  23. Rose CE, Althaus JA, Kaiser DL, Miller ED, Carey RM (1983) Acute hypoxemia and hypercapnia. Increase in plasma catecholamines in conscious dogs. Am J Physiol 245: H924–H929

    PubMed  CAS  Google Scholar 

  24. Jardin F, Farcot JC, Boisante L, Prost JF, Gueret P, Bourdarias JP (1982) Mechanism of paradoxic pulse in bronchial asthma. Circulation 66: 887–894

    Article  PubMed  CAS  Google Scholar 

  25. Squara P, Dhainaut JF, Schremmer B, Sollet JP, Bleichner G (1990) Decreased paradoxic pulse from increased venous return in severe asthma. Chest 97: 377–383

    Article  PubMed  CAS  Google Scholar 

  26. Lloyd TC Jr (1966) Influence of blood pH on hypoxic pulmonary vasoconstriction. J Appl Physiol 21: 358–364

    PubMed  CAS  Google Scholar 

  27. Whittenberger JL, McGregor M, Berglund E, Borst MC (1960) Influence of state of inflation of the lung on pulmonary vascular resistance. J Appl Physiol 15: 878–882

    PubMed  CAS  Google Scholar 

  28. Robotham JL (1981) Cardiovascular disturbances in chronic respiratory insufficiency. Am J Cardiol 47: 941–947

    Article  PubMed  CAS  Google Scholar 

  29. Settle HP, Engel PJ, Fowler NO, et al (1980) Echocardiographic study of the paradoxical arterial pulse in chronic obstructive lung disease. Circulation 62: 1297–1307

    PubMed  Google Scholar 

  30. Jardin F, Gueret P, Prost JF, Farcot JC, Ozier Y, Bourdarias JP (1984) Two-dimensional echocardiographic assessment of left ventricular function in chronic obstructive pulmonary disease. Am Rev Respir Dis 129: 135–142

    PubMed  CAS  Google Scholar 

  31. Gaasch WH, Levine HJ, Quinone MA, Alexander JK (1976) Left ventricular compliance: Mechanisms and clinical implications. Am J Cardiol 38: 645–653

    Article  PubMed  CAS  Google Scholar 

  32. Scharf SM, Brown R, Saunders N, Green LH (1979) Effects of normal and loaded spontaneous inspiration on cardiovascular function. J Appl Physiol 47: 582–590

    PubMed  CAS  Google Scholar 

  33. Scharf SM (1991) Cardiovascular effects of airways obstruction. Lung 169: 1–23

    Article  PubMed  CAS  Google Scholar 

  34. Robotham JL, Badke FR, Kindred MR, Beaton ML (1983) Regional left ventricular performance during normal and obstructed spontaneous inspiration. J Appl Physiol 55: 569–577

    PubMed  CAS  Google Scholar 

  35. Scharf SM, Brown R, Warner KG, Khuri S (1989) Intrathoracic pressures and left ventricular configuration with respiratory maneuvers. J Appl Physiol 66: 481–491

    PubMed  CAS  Google Scholar 

  36. Albert RK, Muramoto A, Caldwell J, Koepsell T, Butler J (1985) Increases in intrathoracic pressure do not explain the rise in left ventricular end-diastolic pressure that occurs during exercise in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 132: 623–627

    PubMed  CAS  Google Scholar 

  37. Butler J, Schrijen F, Henriquez A, Polu JM, Albert RK (1988) Cause of the raised wedge pressure on exercise in chronic obstructive pulmonary disease. Am Rev Respir Dis 138: 350–354

    PubMed  CAS  Google Scholar 

  38. Walley KR, Becker CJ, Hogan RA, Teplinsky K, Wood LDH (1988) Progressive hypoxemia limits left ventricular oxygen consumption and contractility. Circ Res 63: 849–859

    PubMed  CAS  Google Scholar 

  39. Pinsky MR (1989) Effects of changing intrathoracic pressure in the normal and failing heart. In: Scharf SM, Casidy SS (eds) Heart-lung interactions in health and disease. Marcel Dekker, New York, pp 839–876

    Google Scholar 

  40. Schrijen F, Ehrlich W, Permutt S (1975) Cardiovascular changes in conscious dogs during spontaneous deep breaths. Pflugers Arch 355: 205–215

    Article  PubMed  CAS  Google Scholar 

  41. Scharf SM, Brown R, Tow D, Parisi AF (1979) Cardiac effects of increased lung volume and decreased pleural pressure in man. J Appl Physiol 47: 257–262

    PubMed  CAS  Google Scholar 

  42. Buda AJ, Pinsky MR, Ingels NB Jr, Daughters GT, Stinson EB, Alderman EL (1979) Effect of intrathoracic pressure on left ventricular performance. N Engl J Med 301: 453–459

    Article  PubMed  CAS  Google Scholar 

  43. Viola AR, Puy RJM, Goldman E (1990) Mechanisms of pulsus paradoxus in airway obstruction. J Appl Physiol 68: 1927–1931

    PubMed  CAS  Google Scholar 

  44. Karam M, Wise RA, Natarajan TK, Permutt S, Wagner HN (1984) Mechanisms of decreased left ventricular stroke volume during inspiration in man. Circulation 69: 866–873

    Article  PubMed  CAS  Google Scholar 

  45. Brinker JA, Weiss JL, Lappé DL, et al (1980) Leftwards septal displacement during right ventricular loading in man. Circulation 61: 626–633

    PubMed  CAS  Google Scholar 

  46. Peters J, Kindred MK, Robotham JM (1988) Transient analysis of cardiopulmonary interactions. II. Systolic events. J Appl Physiol 64: 1518–1526

    PubMed  CAS  Google Scholar 

  47. Peters J, Kindred MK, Robotham JL (1988) Transient analysis of cardiopulmonary interactions. I. Diastolic events. J Appl Physiol 64: 1506–1517

    PubMed  CAS  Google Scholar 

  48. Robotham JL, Stuart RS, Doherty K, Borkon AM, Baumgartner W (1988) Effects of changes in left ventricular loading and pleural pressure on mitral flow. J Appl Physiol 65: 1662–1675

    PubMed  CAS  Google Scholar 

  49. Robotham JL, Stuart RS, Doherty K, Borton AM, Baumgartner W (1988) Mitral and aortic flows during spontaneous respiration in dogs. Anesthesiology 69: 516–526

    Article  PubMed  CAS  Google Scholar 

  50. Takata M, Mitzner W, Robotham JL (1990) Influence of the pericardium on ventricular loading during respiration. J Appl Physiol 68: 1640–1650

    PubMed  CAS  Google Scholar 

  51. Robotham JL, Wise RA, Bromberger-Barnea B (1985) Effects of changes in abdominal pressure on left ventricular performance and regional blood flow. Crit Care Med 13: 803–809

    Article  PubMed  CAS  Google Scholar 

  52. Pouleur H, Covell JW, Ross J Jr (1980) Effects of nitroprusside on venous return and central blood volume in the absence and presence of acute heart failure. Circulation 61: 328–337

    PubMed  CAS  Google Scholar 

  53. Räsänen J, Heikkila J, Downs J, Nikki P, Vaisänen I, Viitanen A (1985) Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. Am J Cardiol 55: 296–300

    Article  PubMed  Google Scholar 

  54. Pinsky MR, Matuschak GM, Klain M (1985) Determinants of cardiac augmentation by elevations in intrathoracic pressure. J Appl Physiol 58: 1189–1198

    PubMed  CAS  Google Scholar 

  55. Pinsky MR, Summer WR (1983) Cardiac augmentation by phasic high intrathoracic pressure support in man. Chest 84: 370–375

    Article  PubMed  CAS  Google Scholar 

  56. Pinsky MR, Matuschak GM, Bernardi L, Klain M (1986) Hemodynamic effects of cardiac cycle-specific increases in intrathoracic pressure. J Appl Physiol 60: 604–612

    PubMed  CAS  Google Scholar 

  57. Oswalt CE, Gates GA, Holstrom FMG (1977) Pulmonary edema as a complication of acute upper airway obstruction. J Am Med Assoc 238: 1833–1835

    Article  CAS  Google Scholar 

  58. Stradling JR, Bolton P (1982) Upper airways obstruction as cause of pulmonary edema. Lancet 1: 1353–1354

    Article  PubMed  CAS  Google Scholar 

  59. Sofer S, Bar-Ziv J, Scharf SM (1984) Pulmonary edema following relief of upper airway obstruction. Chest 86: 401–403

    Article  PubMed  CAS  Google Scholar 

  60. Stalcup SA, Mellins RB (1977) Mechanical forces producing pulmonary edema in acute asthma. N Engl J Med 297: 592–596

    Article  PubMed  CAS  Google Scholar 

  61. Lemaire F, Teboul JL, Cinotti L, et al (1988) Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation. Anesthesiology 69: 171–179

    Article  PubMed  CAS  Google Scholar 

  62. Permutt S (1988) Circulatory effects of weaning from mechanical ventilation: The importance of transdiaphragmatic pressure. Anesthesiology 69: 157–160

    Article  PubMed  CAS  Google Scholar 

  63. Torres A, Reyes A, Roca J, Wagner PD, Rodriguez-Roisin R (1989) Ventilation-perfusion mismatching in chronic obstructive pulmonary disease during ventilator weaning. Am Rev Respir Dis 140: 1246–1250

    Article  PubMed  CAS  Google Scholar 

  64. Teboul JL, Richard C (1991) Acute left ventricular function in COPD patients during weaning from mechanical ventilation. In: Vincent JL (ed) Update in intensive care and emergency medicine Vol 14. Springer-Verlag, Berlin, pp 297–305

    Google Scholar 

  65. Hurford WE, Lynch KE, Strauss HW, Lowenstein E, Zapol WM (1991) Myocardial perfusion as assessed by Thallium 201 scintigraphy during discontinuation of mechanical ventilation in ventilator-dependent patients. Anesthesiology 74: 1007–1016

    Article  PubMed  CAS  Google Scholar 

  66. Valtier B, Teboul JL, Rekik N, Lemaire F (1989) Enoximone eases weaning from mechanical ventilation in patients with coronary artery disease. Am Rev Respir Dis 139 (Suppl): 96 (Abst)

    Google Scholar 

  67. Richard C, Teboul JL, Archambaud F, Hébert JL, Michaut P, Auzépy P (1995) Left ventricular function during weaning of patients with chronic obstructive pulmonary disease. Intensive Care Med (in press)

    Google Scholar 

  68. Sananes R, Richard C, Teboul JL, Piganeau M, Dépret J, Auzépy P (1990) Echocardiographic evaluation of end-systolic wall stress during weaning from mechanical ventilation. Intensive Care Med 16 (Suppl): 229 (Abst)

    Article  Google Scholar 

  69. Teboul JL, Abrouk F, Lemaire F (1988) Right ventricular function in COPD patients during weaning from mechanical ventilation. Intensive Care Med 14: 483–485

    Article  PubMed  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Teboul, J.L., Mercat, A., Richard, C. (1995). Left Ventricular Function in COPD. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 1995. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79154-3_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79154-3_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58256-4

  • Online ISBN: 978-3-642-79154-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics