Effect of Clindamycin in a New Standardized Animal Model for Chronic Abscess-Forming Peritonitis
To evaluate our new standardized animal model for chronic abscess-forming peritonitis we studied the effect of clindamycin. The advantages of our new model are standardization, reproducibility, and low lethality in the first 14 days . As a consequence we could study the course of peritonitis with normal clinical parameters, and we did not have the disadvantage of other animal models for intraabdominal sepsis, namely uncontrollable early lethality through endotoxic shock [3–5].
KeywordsEndotoxic Shock Intraabdominal Abscess Intraabdominal Sepsis Standardize Animal Model Peritoneal Abscess
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