Role and Measurement of Endotoxin in Septic Shock

  • R. Urbaschek
  • K.-P. Becker
  • R. S. McCuskey
  • B. Urbaschek
Conference paper

Abstract

The development of severe septicemia is a major complication in patients after multiple trauma, burn trauma, or abdominal surgery. In spite of modern surgical procedures, constant improvement in intensive care medicine, and new antimicrobial agents, the incidence and lethality rate of patients developing gram-negative sepsis remain high.

Keywords

Permeability Toxicity Phenol Polysaccharide Serotonin 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Levin J, Bang FB (1964) Bull Johns Hopkins Hosp 115:265–274PubMedGoogle Scholar
  2. 2.
    Ditter B, Becker K-P, Urbaschek R, Urbaschek B (1983) Arzneimittelforschung 33:681–687PubMedGoogle Scholar
  3. 3.
    Becker K-P (1993) Zum Endotoxinnachweis mit Limulus Amöbozyten Lysat. Dissertation, University of HeidelbergGoogle Scholar
  4. 4.
    Urbaschek B, Becker KP, Ditter B, Urbaschek R (1985) In: Leive L (ed) Microbiology-1985. American Society of Microbiology, Washington, pp 39–43Google Scholar
  5. 5.
    Prior RB (ed) Clinical applications of the limulus amoebocyte lysate test. CRC, Boca RatonGoogle Scholar
  6. 6.
    Cavaillon J-M, Munoz C, Fitting C, Misset B, Carlet J (1992) Circ Shock 38:145–152PubMedGoogle Scholar
  7. 7.
    Urbaschek B, Versteyl R (1965) Nature 207:763–764PubMedCrossRefGoogle Scholar
  8. 8.
    Nowotny A (ed) (1983) Beneficial effects of endotoxins. Plenum, New YorkGoogle Scholar
  9. 9.
    Urbaschek R, Urbaschek B (1987) Rev Infect Dis 9:607–615CrossRefGoogle Scholar
  10. 10.
    McCuskey RS, Urbaschek R, McCuskey PA, Urbaschek B (1987) Rev Infect Dis 9:616–619CrossRefGoogle Scholar
  11. 11.
    Liu Z, Simpson RJ, Cheers C (1992) Infect Immun 60:4402–4406PubMedGoogle Scholar
  12. 12.
    Urbaschek R (1993) Prog Med Microbiol 4:1–11Google Scholar
  13. 13.
    Ikemura K, Ikegami K, Shimazu T, Yoshioka T, Sugimoto T (1989) J Clin Microbiol 27:1965–1968PubMedGoogle Scholar
  14. 14.
    Urbaschek R, Becker K-P (1993) Infusionsther Transfusionsmed 20:16–20PubMedGoogle Scholar
  15. 15.
    Obayashi T, Tamara S, Tanaka S (1985) Clin Chim Acta 149:55–65PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • R. Urbaschek
  • K.-P. Becker
  • R. S. McCuskey
  • B. Urbaschek

There are no affiliations available

Personalised recommendations