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Modifizierte Pasteurisierung zur Erhöhung der Virussicherheit eines hochreinen Faktor VIII-Konzentrats

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24. Hämophilie-Symposion

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Zusammenfassung

Die Virussicherheit plasmatischer Gerinnungspräparate beruht auf drei unterschiedlichen Prinzipien:

  • sorgfältige Spenderauswahl und Testung jeder Einzelspende;

  • Einsatz hochentwickelter Technologien zur Virusinaktivierung;

  • GMP-gerechte Herstellung unter Erfüllung der notwendigen Anforderungen an die Qualitätskontrolle.

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Literatur

  1. Richtlinien zur Blutgruppenbestimmung und Bluttransfusion (1991) Deutscher Ärzteverlag, Köln

    Google Scholar 

  2. Suomela H (1993) Inactivation of viruses in blood and plasma products. Transfus Med Rev 7 (l): 42–57

    Article  PubMed  CAS  Google Scholar 

  3. Fricke WA, Lamb MA (1993) Viral safety of clotting factor concentrates. Sem Thromb Haemost 19 (1): 54–61

    Article  CAS  Google Scholar 

  4. Goudemand J, Parquet A, Boulanger P, Goudemand J (1993) Study of viral safety, immune functions and inhibitor development in a cohort of 22 haemophiliac children only treated with an ion exchange purified FVIII concentrate. Br J Haem 84 (Suppl 1): 15

    Google Scholar 

  5. Mannucci PM (1993) Clinical evaluation of viral safety of coagulation factor VIII and IX concentrates. Vox Sang 64: 197–203

    Article  PubMed  CAS  Google Scholar 

  6. Guerois C, Parquet A, Gazengel C et al (1990) Anti HCV antibodies studies in a cohort of French Haemophiliacs patients: high incidence of an anti-HCV and probable prevention with SD concentrates. XIX International Congress of the World Federation of Hemophilia, August 14–19, 1990

    Google Scholar 

  7. Validation of virus removal and inactivation procedures. Note for guidance (1991) Committee for Proprietary Medical Products: Ad Hoc Working Party on Biotechnology/ Pharmacy and Working Party on Safety medicines. Biologicals 19: 247–251

    Google Scholar 

  8. Hollinger FB, Ticehurst J (1990) Hepatitis A virus. In: Fields BN, Knipe DM (eds) Virology, 2nd ed. Raven Press, New York, pp 631–667

    Google Scholar 

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Authors
  1. L. Biesert
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  2. H. Suhartono
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  3. L. Wang
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  4. H. Rübsamen
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Editor information

Editors and Affiliations

  1. Abteilung für Angiologie, Zentrum der Inneren Medizin, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, D-60590, Frankfurt am Main, Germany

    Inge Scharrer

  2. Hämostaseologische Abteilung, Medizinische Klinik, Klinikum Innenstadt der Ludwig-Maximilians-Universität, Ziemssenstraße 1a, D-80336, München, Germany

    Wolfgang Schramm

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© 1994 Springer-Verlag Berlin Heidelberg

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Biesert, L., Suhartono, H., Wang, L., Rübsamen, H. (1994). Modifizierte Pasteurisierung zur Erhöhung der Virussicherheit eines hochreinen Faktor VIII-Konzentrats. In: Scharrer, I., Schramm, W. (eds) 24. Hämophilie-Symposion. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79009-6_53

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  • DOI: https://doi.org/10.1007/978-3-642-79009-6_53

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57999-1

  • Online ISBN: 978-3-642-79009-6

  • eBook Packages: Springer Book Archive

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