Management of Patients with Antiphospholipid Antibodies

  • B. Alving
Conference paper


Antiphospholipid antibodies, which are detected in coagulation assays as lupus anticoagulants (LA) or in solid-phase ELISAs as anticardiolipin antibodies (ACA), have been recognized in many different clinical settings for the past forty years. The antibodies appear to be an incidental finding in patients who have infections or who are using medications such as procainamide or quinidine. However, in patients who have systemic lupus erythematosus (SLE) or other autoimmune connective tissue disorders or in those who may have no apparent autoimmune disorder, the presence of antiphospholipid antibodies indicates an increased risk for thrombosis, fetal loss, or thrombocytopenia.


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© Springer-Verlag Berlin Heidelberg 1994

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  • B. Alving

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