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A Model of the Leukocyte Migration Through Solid Tissue

  • Boguslaw A. Skierczynski
  • Shunichi Usami
  • Richard Skalak
Part of the NATO ASI Series book series (volume 84)

Abstract

Neutrophils are defensive cells that are recruited from the blood into damaged or inflamed tissues by chemotactic agents. Ligand-receptor interactions at the cell surface elicit adhesion, locomotion, granule exocytosis, and the respiratory burst [Baggiolini and Kernen, 1992]. In vitro analysis shows that these responses are controlled at several levels of intracellular signal transduction processes. In this introduction we first review some of the biochemical events associated with these responses.

Keywords

Actin Filament Actin Polymerization Adhesion Receptor Actin Network Cell Locomotion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • Boguslaw A. Skierczynski
    • 1
  • Shunichi Usami
    • 2
  • Richard Skalak
    • 1
  1. 1.Institute for Biomedical EngineeringUniversity of California, San DiegoLa JollaUSA
  2. 2.Institute of Biomedical ScienceAcademia SinicaTaiwan, ROC

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