Abstract
Nearly all types of cells, prokaryotic and eukaryotic, can respond to the mechanical environment. This environment may be due to environmental stresses (e.g. wind, or activity, perhaps also gravity) or vibrations (e.g. sound), the difference being merely the amplitudes and the frequencies involved. The response of so called non-excitable cells will be discussed here, since the biophysics of various sensory cells have been well described in the literature. Several transduction mechanisms have been proposed, listed in table 1. Of these hypotheses the first, strain related potentials, will not be discussed here, due to lack of space and for lack of solid support.
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References
Ando J, Komatsuda T, Kamiya A. (1988). Cytoplasmic calcium response to fluid shear stress in cultured vascular endothelial cells. In Vitro 24, 871–877
Bagi, C., & Burger, E.H. (1989). Mechanical stimulation by intermittent compression stimulates sulfate incorporation and matrix mineralization in fetal mouse long-bone rudiments under serum-free conditions. Calcif Tissue Int 45, 342–347
Bassett, C.A.L. & Becker, R.O. (1962). Generation of Electric Potentials by Bone in Response to Mechanical stress. Science 137, 1063–1064
Binderman, I. Zor, U. Kaye, A.M. Shimshoni, Z. Harell, A. & Somjen D. (1988). The transduction of mechanical force into biochemical events in bone cells may involve activation of phospholipase A2. Calc. Tiss. Int 42, 261–266
Canfield, J. & Eaton, C. (1990). Swimbladder acoustic pressure transduction initiates Mauthnermediated escape Nature, 347: 760–762, 1990
Davidovitch, Y. Shanfeld, J. L. Montgomery, P. C. Lally, E. Laster, L. Fürst, L. & Korostoff E. (1984). Biochemical Mediators of the Effects of Mechanical Forces and Electric Currents on Mineralised Tissues Calif. Tissue Int 36, 86–97
Davidson, R.M. Tatakis, D.W. & Auerbach, A.L. (1990). Multiple forms of mechanosensitive ion channels in osteoblast-like cells. Eur. J. Physiol (Pflügers Archiv) 416, 646–651
Duncan, R. & Misler, S. (1989). Volt age-activated and stretch-activated Ba††conducting channels in an osteoblast-like cell line (UMR 106) FEBS Lett. 251, 17–21
Gehring, C.A., Williams, D.A. Cody, S.H. & Parish R.W. (1990). Phototropism and geotropism in maize coleoptiles are spatially correlated with increases in cytosolic free calcium Nature 345, 528–530
Gjelsvik A. (1973). Bone Remodeling and Piezoelectricity-I. J.Biomechanics 6, 69–77
Golz, R. & Thurm, U. (1991). Cytoskeleton-membrane interactions in the cnidocil complex of hydrozoan nematocytes Cell Tiss. Res 263, 573–583
Guharay, F. & Sachs F. (1984). Stretch activated K+ channels in muscle cell membranes as mechanotransducers? J. Physiol. Lond 352, 685–701.
Hall, A.C. Urban, J.P.G. & Gehl, K.A. (1991). The effects of hydrostatic pressure on matrix synthesis in articular cartilage. J. Orthop. Res 9, 1–10
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© 1994 Springer-Verlag Berlin Heidelberg
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Jones, D.B., Leivseth, G. (1994). Strain Transduction in Non-Excitable Cells. In: Akkaş, N. (eds) Biomechanics of Active Movement and Division of Cells. NATO ASI Series, vol 84. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78975-5_17
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DOI: https://doi.org/10.1007/978-3-642-78975-5_17
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