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Molecular Biology of Mitochondrial Transport Systems pp 281–296Cite as

Structure and Function of the VDAC Ion Channel

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Part of the book series: NATO ASI Series ((ASIH,volume 83))

Abstract

Mitochondria function within the cytoplasm of eukaryotic cells separated from the cytoplasm by a membranous barrier, the mitochondrial outer membrane. Permeability pathways in this membrane, such as the VDAC channels, can be viewed both as a means by which metabolites may travel from one compartment to the other and as a means of controlling the flux of such metabolites. Both of these functions depend on the properties of the permeating pathways, such as the VDAC channels. By examining in detail the properties of VDAC one should obtain insights into its role in mitochondrial function.

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Author information

Authors and Affiliations

  1. Department of Zoology, University of Maryland, College Park, MD, 20742, USA

    Marco Colombini

Authors
  1. Marco Colombini
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Editor information

Editors and Affiliations

  1. Vollum Institute for Advanced Biomedical Research, Oregon Health Sciences University, 3181 S. W. Sam Jackson Park Rd., Portland, OR, 97201, USA

    Michael Forte

  2. Department of Zoology, University of Maryland, College Park, MD, 20742, USA

    Marco Colombini

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© 1994 Springer-Verlag Berlin Heidelberg

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Colombini, M. (1994). Structure and Function of the VDAC Ion Channel. In: Forte, M., Colombini, M. (eds) Molecular Biology of Mitochondrial Transport Systems. NATO ASI Series, vol 83. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78936-6_20

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  • DOI: https://doi.org/10.1007/978-3-642-78936-6_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78938-0

  • Online ISBN: 978-3-642-78936-6

  • eBook Packages: Springer Book Archive

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