Serotonin and Smooth Muscle

  • A. L. Killam
  • M. L. Cohen
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 111)


Serotonin as an endogenous neurotransmitter has been implicated in the pathophysiology of diseases involving many smooth muscle systems including hypertension, migraine, Raynaud’s phenomenon, vasospasm of the coronary and the cerebral vasculature, gut motility disorders, and dysfunction of genitourinary smooth muscle. Compared to our knowledge of the cholinergic and adrenergic systems, the precise involvement of serotonin in both the physiological and pathological functions of smooth muscle has remained elusive.


Contractile Response Serotonin Receptor Porcine Coronary Artery Serotonin Receptor Subtype Esophageal Smooth Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • A. L. Killam
  • M. L. Cohen

There are no affiliations available

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