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Proteolytic Enzymes and Wound Healing pp 31–48Cite as

Surgical Versus Enzymatic Débridement

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Summary

Early surgical escharectomy has proven advantages in the treatment of extensive burns. It is justified mainly for extensive burns. The main indication for treatment with proteolytic enzymes is small (< 5 cm) second-degree burn wounds. Treatment with proteolytic enzymes is an alternative to early escharectomy in special cases: limited burns on the flexor surfaces of joints, hands, groin, heel, dorsal surface of the forefoot, and subunte of the face. Enhancement of the inflammatory phase of wound healing by proteolytic enzymes seems to be possible only in very early phases of wound healing, Treatment in this period results In a more rapid cleansing of burn wounds. Clinical experience has proved that the treatment of recipient sites by proteolytic enzymes leads to satisfying results concerning graft acceptance and later scar control.

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Author information

Authors and Affiliations

  1. Institute of Plastic Surgery, University of Milan, 3-20162, Milan, Italy

    L. Donati, M. Colonna & S. Garbin

  2. Department of Microbiology, Niguarda Ca′ Granda Hospital, Piazza Ospedale Maggiore, 3-20162, Milan, Italy

    E. Magliano

Authors
  1. L. Donati
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  2. E. Magliano
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  3. M. Colonna
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  4. S. Garbin
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Editor information

Editors and Affiliations

  1. Academic Medical Center, Department of Dermatology, University of Amsterdam, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands

    W. Westerhof

  2. Universitäts-Hautklinik, Hauptstr. 7, 79104, Freiburg i. Br., Germany

    W. Vanscheidt

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© 1994 Springer-Verlag Berlin Heidelberg

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Donati, L., Magliano, E., Colonna, M., Garbin, S. (1994). Surgical Versus Enzymatic Débridement. In: Westerhof, W., Vanscheidt, W. (eds) Proteolytic Enzymes and Wound Healing. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78891-8_4

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  • DOI: https://doi.org/10.1007/978-3-642-78891-8_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57816-1

  • Online ISBN: 978-3-642-78891-8

  • eBook Packages: Springer Book Archive

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