Aetiological Factors in Benign Prostatic Hyperplasia

  • S. Shepherd

Abstract

Benign prostatic hyperplasia (BPH) is emerging as a significant public health problem as the high prevalence of the disease is becoming increasingly recognised. In order to minimise the morbidity, mortality and economic burden from BPH it is important to delineate its causal factors so that appropriate intervention is undertaken where feasible. The aetiology of BPH is not fully understood, and additional research at biochemical, pathological, clinical and epidemiological levels is required. This chapter outlines the contribution of epidemiology to elucidating the aetiological factors known to date. It begins with a general discussion on risk factors and disease causation. This is followed by a review of the important methodological difficulties encountered in the investigation of BPH. Finally, the evidence for individual risk factors is presented.

Keywords

Obesity Estrogen Adenoma Coherence Testosterone 

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© Springer-Verlag Berlin Heidelberg 1995

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  • S. Shepherd

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