Abstract
Approximately 15% of strokes involve the vertebrobasilar circulation. Acute bilateral vertebral artery or basilar artery thrombosis is considered one of the most important life-threatening emergencies. The prognosis in untreated basilar occlusion is known to be poor, and it is rarely survived [1,4]. Anticoagulation as well as intravenous systemic thrombolysis with recombinant tissue plasminogen activator (rTPA) have shown unsatisfactory results [5]. Local intra-arterial fibrinolysis is currently regarded as the method of choice in vertebrobasilar occlusion [3].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Archer CR, Horenstein S (1977) Basilar artery occlusion. Clinical and radiological correlation. Stroke 8:383–390
Ferbert A, Brückmann H, Drummen R (1990) Clinical features of proven basilar artery occlusion. Stroke 21:1135–1142
Hacke W, Hirschberg M (1992) Zerebrovaskuläre Verschlüsse. Indikation zur Thrombolysetherapie. Internist 33:241–246
Hacke W, Zeumer H, Ferbert A, Brückmann H, del Zoppo GJ (1988) Intraarterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke 19:1216–1222
Von Kummer R, Forsting M, Sartor K, Hacke W (1991) Intravenous plasminogen activator in acute stroke. In: Hacke W, del Zoppo GJ, Hirschberg M (eds) Thrombolytic therapy in acute ischemic stroke. Springer, Berlin Heidelberg New York
Zeumer H (1992) Fibrinolysis in cerebrovascular diseases of the central nervous system. In: Vinuela F, van Halbach B, Dion JE (eds) Interventional neuroradiology: endovascular therapy of the central nervous system. Raven, New York, pp 141–151
Zeumer H, Freitag HJ, Zanella F, Thie A, Arning C (1993) Local intra-arterial fibrinolytic therapy in patients with stroke: urokinase versus recombinant tissue plasminogen activator (r-TPA). Neuroradiology 35:159–162
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Schumacher, M., Siekmann, R., Radü, W., Wakhloo, A.K. (1994). Local Intra-arterial Fibrinolytic Therapy in Vertebrobasilar Occlusion. In: Bauer, B.L., Brock, M., Klinger, M. (eds) Cerebellar Infarct. Midline Tumors. Minimally Invasive Endoscopic Neurosurgery (MIEN). Advances in Neurosurgery, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78801-7_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-78801-7_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-57668-6
Online ISBN: 978-3-642-78801-7
eBook Packages: Springer Book Archive