Magnetic Resonance Imaging-Guided Interstitial Laser Therapy in Brain Tumors

  • M. Bettag
  • F. Ulrich
  • T. Kahn
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 22)


Laser-induced interstitial thermotherapy (LITT) is a minimally invasive technique of local brain tumor destruction. The concept of interstitial hyperthermia was first evaluated in experimental studies by Bown in 1983 [6]. For a safe clinical application it is mandatory to define the extent of thermally mediated laser-induced damage to the tissue. Jolesz and coworkers studied the sensitivity of magnetic resonance imaging (MRI) to visualize laser-induced tissue changes [7]. MRI proved to be well suited for monitoring LITT due to its high soft-tissue contrast and its sensitivity for temperature changes. In this paper we report our experiences with MRI-guided LITT in eight patients with intracranial tumors.


Laser Fiber Laser Therapy Perifocal Edema Interstitial Thermotherapy Zonal Architecture 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • M. Bettag
    • 1
  • F. Ulrich
    • 1
  • T. Kahn
    • 2
  1. 1.Neurochirurgische KlinikHeinrich-Heine-Universität DüsseldorfDüsseldorfGermany
  2. 2.Institut für Diagnostische RadiologieHeinrich-Heine-Universität DüsseldorfDüsseldorfGermany

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