Quantisation of Mixed Chimerism in Blood and Bone Marrow
Bone marrow transplantation (BMT) in haemato-oncological patients is a recent area of applied DNA analysis. The determination and quantisation of donor cells in samples of blood or bone marrow in allogenic BMT verifies engraftment and detects relapses, especially if there is no specific marker for the leukaemic disease. Quantisation of components in tissues of different genetic origin might also be valuable in mixed lymphoid chimerism (MC) after liver transplantation or in zygosity studies of twins.
KeywordsAgarose Electrophoresis Nylon BCIP
Unable to display preview. Download preview PDF.