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Quantisation of Mixed Chimerism in Blood and Bone Marrow

  • C. Simon
  • C.-C. Loeliger
  • A. R. Zander
  • P. Kuehnl
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 5)

Abstract

Bone marrow transplantation (BMT) in haemato-oncological patients is a recent area of applied DNA analysis. The determination and quantisation of donor cells in samples of blood or bone marrow in allogenic BMT verifies engraftment and detects relapses, especially if there is no specific marker for the leukaemic disease. Quantisation of components in tissues of different genetic origin might also be valuable in mixed lymphoid chimerism (MC) after liver transplantation or in zygosity studies of twins.

Keywords

Bone Marrow Transplantation Allogenic Bone Marrow Transplantation Severe Combine Immunodeficiency Mixed Chimerism Severe Combine Immunodeficiency Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • C. Simon
    • 1
  • C.-C. Loeliger
    • 1
  • A. R. Zander
    • 2
  • P. Kuehnl
    • 1
  1. 1.Dept. of Transfusion Medicine and Transplantation ImmunologyUniversity of HamburgGermany
  2. 2.Bone Marrow Transplantation UnitUniversity of HamburgGermany

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