Study of the APO B Polymorphism in Tuscany (Italy)

  • R. Domenici
  • S. Fornaciari
  • M. Nardone
  • M. F. Ricciardi
  • I. Spinetti
  • M. Venturi
  • M. Bargagna
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 5)

Abstract

The APO B VNTR locus is located next to the 3′ end of the apolipoprotein B gene and consists of a series of AT rich tandem repeats, each 14–16 bp long (for a review about the genetic relationship between the 3′-VNTR and diallelic apolipoprotein B gene polymorphism, see Renges et al, 1992; for a recent proposal of a molecular model, see Desmarais et al 1993). Its polymorphism was described by Boerwinkle et al (1989) and by Ludwig et al (1989) using the PCR technique. Since then, the APO B has become a genetic marker quite frequently used in forensic practice.

Keywords

Agarose Electrophoresis Polyacrylamide 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • R. Domenici
    • 1
  • S. Fornaciari
    • 1
  • M. Nardone
    • 1
  • M. F. Ricciardi
    • 1
  • I. Spinetti
    • 1
  • M. Venturi
    • 1
  • M. Bargagna
    • 1
  1. 1.Department of Biomedicine — Section of Legal MedicineUniversity of PisaPisaItaly

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