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Herz- und kreislaufwirksame Medikamente in Anästhesie, Intensiv- und Notfallmedizin pp 3–45Cite as

Pathophysiologie der Myokardischämie

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Part of the book series: Klinische Anästhesiologie und Intensivtherapie ((KAI,volume 47))

Zusammenfassung

Die Myokardischämie wird traditionell als ein Mißverhältnis zwischen dem Energieangebot durch die Koronardurchblutung und dem Energiebedarf im wesentlichen für die Myokardkontraktion verstanden. Die Befunde, die diese Vorstellung stützen, haben jedoch dem grundsätzlich regionalen Charakter der Myokardischämie nicht Rechnung getragen. Einerseits wurde in vielen Fällen nicht die regionale myokardiale Durchblutung gemessen, andererseits wurde der regionale Energiebedarf der ischämischen Region aus dem Bedarf des gesamten Herzens oder dem Bedarf nichtischämischer Areale geschätzt. Die Koronargefäße werden in der klassischen Vorstellung der Myokardischämie als maximal weitgestellt angesehen, und Veränderungen der Myokarddurchblutung werden deshalb der extravaskulären Kompression zugeschrieben.

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Authors
  1. D. Baumgart
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  2. G. Heusch
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Editors and Affiliations

  1. Universität Ulm, Steinhövelstr. 9, D-89075, Ulm, USA

    Friedrich Wilhelm Ahnefeld

  2. Klinik für Anästhesiologie, Johannes Gutenberg-Universitä, Langenbeckstr. 1, 55101, Mainz, Deutschland

    Wolfgang Dick

  3. Medizinische Klinik, Innere Medizin III, Universität zu Köln, Joseph-Stelzmann-Str. 9, D-50924, Köln, Deutschland

    E. Erdmann

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© 1995 Springer-Verlag Berlin Heidelberg

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Baumgart, D., Heusch, G. (1995). Pathophysiologie der Myokardischämie. In: Ahnefeld, F.W., Dick, W., Erdmann, E. (eds) Herz- und kreislaufwirksame Medikamente in Anästhesie, Intensiv- und Notfallmedizin. Klinische Anästhesiologie und Intensivtherapie, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78777-5_1

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  • DOI: https://doi.org/10.1007/978-3-642-78777-5_1

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