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Risk of Developing Cutaneous Malignant Melanoma in Atypical-Mole Syndrome: New York University Experience and Literature Review

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Skin Cancer: Basic Science, Clinical Research and Treatment

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 139))

Abstract

The presence of atypical moles (AM) is considered to be a marker for an increased risk of developing cutaneous malignant melanoma (MM). The extent to which individuals with the atypical-mole syndrome (AMS) are at risk for developing MM is unknown. We present a review of the world literature and of our experience at New York University. We conclude that the presence of AMS in Caucasians significantly increases the risk of developing MM, regardless of geographic location. A further increase in MM risk is noted if there is a personal and/or family history of MM.

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Author information

Authors and Affiliations

  1. Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 550 First Avenue, New York, NY, 10016, USA

    J. Slade, T. G. Salopek (lecturer), A. A. Marghoob, A. W. Kopf & D. S. Rigel

  2. Oncology Section, Charles C Harris Skin and Cancer Pavilion, New York University Medical Center, New York, USA

    J. Slade, T. G. Salopek (lecturer), A. A. Marghoob, A. W. Kopf & D. S. Rigel

  3. New York University Melanoma Cooperative Group, New York, USA

    J. Slade, T. G. Salopek (lecturer), A. A. Marghoob, A. W. Kopf & D. S. Rigel

  4. Department of Dermatology, State University of New York at Stony Brook, USA

    A. A. Marghoob

  5. Division of Dermatology, University of Alberta, Edmonton, Canada

    T. G. Salopek (lecturer)

Authors
  1. J. Slade
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  2. T. G. Salopek
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  3. A. A. Marghoob
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  4. A. W. Kopf
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  5. D. S. Rigel
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Editor information

Editors and Affiliations

  1. University Department of Dermatology Medical Centre Benjamin Franklin, Freie Universität Berlin, Hindenburgdamm 30, 12200, Berlin, Germany

    Claus Garbe , Stefan Schmitz  & Constantin E. Orfanos ,  & 

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© 1995 Springer-Verlag Berlin · Heidelberg

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Slade, J., Salopek, T.G., Marghoob, A.A., Kopf, A.W., Rigel, D.S. (1995). Risk of Developing Cutaneous Malignant Melanoma in Atypical-Mole Syndrome: New York University Experience and Literature Review. In: Garbe, C., Schmitz, S., Orfanos, C.E. (eds) Skin Cancer: Basic Science, Clinical Research and Treatment. Recent Results in Cancer Research, vol 139. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78771-3_7

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  • DOI: https://doi.org/10.1007/978-3-642-78771-3_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78773-7

  • Online ISBN: 978-3-642-78771-3

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