TRH and Substance P Increase Rat Motoneurone Excitability through a Block of a Novel K+ Conductance
Immunocytochemical studies of the fine localization of endogenously-occurring TRH and substance P in the mammalian spinal cord have shown that these two peptides are present in the terminals of fibres descending from the raphe nucleus and which establish synaptic contacts with the proximal dendrites of motoneurons.1,7. Other nerve cells containing these peptides are found in the spinal dorsal horn.
KeywordsCadmium Barium Acetylcholine Washout Urethane
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