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Chronobiology of Human Bone Marrow

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Biologic Rhythms in Clinical and Laboratory Medicine

Abstract

Bone marrow is the production site for all types of blood cells, which are released into the peripheral blood according to the needs of the body, mediated through different feedback mechanisms. The production occurs as a combination of cell proliferation and gradual maturation, until the end stage is reached with a population of mature cells that can exert their specialized functions but are no longer capable of cell proliferation [1]. It takes approximately 14 days from immature stem cells starting proliferation until mature cells result [2].

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Authors
  1. R. Smaaland
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  2. O. D. Laerum
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Editors and Affiliations

  1. Faculté de Médecine Pitié-Salpétrière, Laboratoire de Biochimie Médicale, 91, Boulevard de l’Hôpital, 75634, Paris Cedex 13, France

    Yvan Touitou (Professor of Biochemistry) (Professor of Biochemistry)

  2. Department of Laboratory Medicine and Pathology, University of Minnesota, 640 Jackson Street, 55101-259, St.Paul, MN, USA

    Erhard Haus (Professor, Chairman) (Professor, Chairman)

  3. Department of Anatomic and Clinical Pathology, St. Paul-Ramsey Medical Center, 640 Jackson Street, 55101-259, St.Paul, MN, USA

    Erhard Haus (Professor, Chairman) (Professor, Chairman)

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© 1992 Springer-Verlag Berlin Heidelberg

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Smaaland, R., Laerum, O.D. (1992). Chronobiology of Human Bone Marrow. In: Touitou, Y., Haus, E. (eds) Biologic Rhythms in Clinical and Laboratory Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78734-8_38

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  • DOI: https://doi.org/10.1007/978-3-642-78734-8_38

  • Publisher Name: Springer, Berlin, Heidelberg

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