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Mikrobiologie und Seroepidemiologie von Helicobacter pylori

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Ökosystem Darm V

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Zusammenfassung

Helicobacter pylori ist in den 10 Jahren seit seiner Entdeckung durch Warren u. Marshall 1992 [64] zunehmend ein Objekt der Forschung von Mikrobiologen, Pathologen und Gastroenterologen geworden. Das Spektrum der bekannten Helicobacter-Spezies umfaßt inzwischen neben H. pylori bereits 8 weitere Arten (Tabelle 1), darunter die früher der Gattung Campylobacter zugeordneten H. fennelliae und H. cinaedi [2]. Der ursächliche Zusammenhang zwischen H.-pylori-Infektion und Gastritis, eine 90 %ige Korrelation mit der peptischen Ulkuskrankheit [4, 27], sowie eine erhebliche Bedeutung als Kofaktor bei der Entstehung des Adenokarzinoms des Magen gilt heute als gesichert [16]. Die Helicobacter-Infektion kann als Prototyp einer chronischen bakteriellen Entzündung gelten. Die Pathogenese dieser chronischen Erkrankung sowie die Infektionsquellen und Übertragungswege des Erregers sind bisher allerdings nur unvollständig geklärt.

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Authors
  1. M. Kist
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Editors and Affiliations

  1. Innere Medizin II, Medizinische Klinik und Poliklinik, Universitätskliniken des Saarlandes, 66421, Homburg/Saar, Deutschland

    Martin Zeitz

  2. Zentrum der Inneren Medizin, Universitätsklinikum, Theodor-Stem-Kai 7, 60596, Frankfurt, Deutschland

    W. F. Caspary

  3. Nationales Referenzzentrum für Enteritiserreger, Hygienisches Institut, Marckmannstraße 129a, 20539, Hamburg, Deutschland

    Jochen Bockemühl

  4. Medizinsche Klinik, Städtisches Krankenhaus Solingen, Postfach, 42719, Solingen, Deutschland

    Gerd Lux

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© 1993 Springer-Verlag Berlin Heidelberg

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Kist, M. (1993). Mikrobiologie und Seroepidemiologie von Helicobacter pylori. In: Zeitz, M., Caspary, W.F., Bockemühl, J., Lux, G. (eds) Ökosystem Darm V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78733-1_23

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  • DOI: https://doi.org/10.1007/978-3-642-78733-1_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57591-7

  • Online ISBN: 978-3-642-78733-1

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