Laser Ablation pp 135-155 | Cite as

Laser Ablation and Laser Desorption Techniques with Fourier-Transform Mass Spectrometry (FTMS)

  • R. L. Hettich
  • C. Jin
Part of the Springer Series in Materials Science book series (SSMATERIALS, volume 28)

Abstract

The advent of pulsed lasers has enabled a variety of experiments to be performed that had previously been impossible. In particular, the combination of lasers with mass spectrometers such as Time-Of-Flight (TOF) mass analyzers provides an experimental method for generating unusual species such as bare-metal clusters as well as desorbing large non-volatile biomolecules. One particular mass analyzer, a Fourier Transform ion cyclotron resonance Mass Spectrometer (FTMS), can easily be interfaced with lasers and has been demonstrated to be quite useful for these studies [6.1]. The extensive ion trapping and ion manipulation capabilities of FTMS can be used to examine the structures and reactivities of ions generated by the laser ablation and laser desorption processes. The focus of this chapter is not to extensively review the literature of laser applications with FTMS, but rather provide a broad overview of some of the types of experiments that can be performed with this technique. In particular, we will illustrate the basic principles of FTMS ion trapping and detection, and then focus on recent developments and applications of laser ablation FTMS for the study of cluster species and laser desorption FTMS for the examination of large biomolecules.

Keywords

Sugar Surfactant Argon Boron Electrophoresis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 6.1
    D. Lubman (ed.): Lasers and Mass Spectrometry (Oxford Univ. Press, New York 1990 )Google Scholar
  2. 6.2
    M.A. May, P.B. Grosshans, A.G. Marshall: Int. J. Mass. Spectrom. Proc. 120, 193 (1991)CrossRefADSGoogle Scholar
  3. 6.3
    F. Hillenkamp, M. Karas, R.C. Beavis, B.T. Chait: Anal. Chem. 63, 1193A (1991)CrossRefGoogle Scholar
  4. 6.4
    A.G. Marshall, L. Schweikhard: Int. J. Mass Spectrom. Ion Proc. 118/119, 37 (1992)Google Scholar
  5. 6.5
    A.G. Marshall, P.B. Grosshans: Anal. Chem. 63, 215A (1991)CrossRefGoogle Scholar
  6. 6.6
    E.R. Williams, K.D. Henry, F.W. McLafferty: J. Am. Chem. Soc. 112, 6157 (1990)CrossRefGoogle Scholar
  7. 6.7
    F.W. McLafferty (ed.): Tandem Mass Spectrometry ( Wiley, New York 1983 )Google Scholar
  8. 6.8
    E.R. Williams, F.W. McLafferty: J. Am. Soc. Mass Spectrom. 1, 361 (1990).CrossRefGoogle Scholar
  9. 6.9
    P. Jena, B.K. Rao, S.N. Khanna (eds.): Physics and Chemistry of Small Clusters ( Plenum, New York 1987 )Google Scholar
  10. 6.10
    E.L. Muetterties: Bull. Soc. Chem. Belg. 84, 959 (1975)CrossRefGoogle Scholar
  11. 6.11
    E. Shustorovich, R.C. Baetzold, E.L. Muetterties: J. Phys. Chem. 876, 1100 (1983)CrossRefGoogle Scholar
  12. 6.12
    R.E. Smalley: In Comparison of Ab-initio Quantum Chemistry with Experiment for Small Molecules: State of the Art, ed. by R.J. Bartlett ( Reidel, New York 1985 ) p. 53Google Scholar
  13. 6.13
    R.E. Smalley: In Metal-Metal Bonds and Clusters in Chemistry and Catalysis, ed. by J.P. Frackler ( Plenum, New York 1989 ) p. 249Google Scholar
  14. 6.14
    R.P. Andres, R.S. Averback, W.L. Brown, L.E. Brus, W.A. Goddard, A. Kaldor, S.G. Louie, M. Moscovits, P.S. Peercy, S.J. Riley, R.W. Siegel, F. Spaepen, Y. Wang: J. Mater. Res. 4, 704 (1989)CrossRefADSGoogle Scholar
  15. 6.15
    M.E. Tremblay, B.W. Smith, M.B. Long, J.D. Winefordner: Spectrosc. Lett. 20, 311 (1987)CrossRefADSGoogle Scholar
  16. 6.16
    M.L. Mandich, W.D. Reents Jr., V.E. Bondybey: J. Phys. Chem. 90, 2315 (1986)CrossRefGoogle Scholar
  17. 6.17
    W.D. Reents Jr., M.L. Mandich, V.E. Bondybey: Chem. Phys. Lett. 125, 324 (1986)CrossRefADSGoogle Scholar
  18. 6.18
    W.D. Reents Jr., M.L. Mandich, V.E. Bondybey: Chem. Phys. Lett. 131, 1 (1986)CrossRefADSGoogle Scholar
  19. 6.19
    O’Keefe, M.M. Ross, A.P. Baronavski: Chem. Phys. Lett. 130, 17 (1986)CrossRefADSGoogle Scholar
  20. 6.20
    S.W. McElvany, W.R. Creasy, A.O. O’Keefe: J. Chem. Phys. 85, 632 (1986)CrossRefADSGoogle Scholar
  21. 6.21
    S.W. McElvany, H.H. Nelson, A.P. Baronovski, P. Andrew, C. H. Clifford, J.R. Eyler: Chem. Phys. Lett. 134, 214 (1987)CrossRefADSGoogle Scholar
  22. 6.22
    W.R. Creasy, J.T. Brenna: Chem. Phys. 126, 453 (1988)CrossRefADSGoogle Scholar
  23. 6.23
    R.L. Hettich: J. Am. Chem. Soc. I II, 8582 (1989)Google Scholar
  24. 6.24
    T.G. Dietz, M.A. Duncan, D.E. Powers, R.E. Smalley: J. Chem. Phys. 74, 6511 (1981)CrossRefADSGoogle Scholar
  25. 6.25
    D.E. Powers, S.G. Hanson, M.E. Geusic, A.C. Puiu, J.B. Hopkins, T.G. Dietz, M.A. Duncan, P.R.R. Langridge-Smith, R.E. Smalley: J. Phys. Chem. 86, 2556 (1982).CrossRefGoogle Scholar
  26. 6.26
    S.J. Riley, E.K. Parks, C.R. Mao, L.G. Pobo, S. Wexler: J. Phys. Chem. 86, 3911 (1982)CrossRefGoogle Scholar
  27. 6.27
    V.E. Bondybey, J.H. English: J. Chem. Phys. 80, 568 (1984)CrossRefADSGoogle Scholar
  28. 6.28
    J.M. Alford, F.K. Weiss, R.T. Laaksonnen, R.E. Smalley: J. Phys. Chem. 90, 4480 (1986)CrossRefGoogle Scholar
  29. 6.29
    S. Maruyama, L.R. Anderson, R.E. Smalley: Rev. Sci. Instrum. 61, 3686 (1990)CrossRefADSGoogle Scholar
  30. 6.30
    D.B. Jacobson, B.S. Freisen J. Am. Chem. Soc. 106, 5351 (1984)CrossRefGoogle Scholar
  31. 6.31
    R.L. Hettich, B.S. Freisen In Fourier Transform Mass Spectrometry: Evolution, Innovation, and Applications, ed. by M.V. Buchanan, Vol. 359 (Am. Chem. Soc. Washington, DC 1987 ) p. 155Google Scholar
  32. 6.32
    D.B. Jacobson, B.S. Freisen J. Am. Chem. Soc. 108, 27 (1986)CrossRefGoogle Scholar
  33. 6.33
    R.L. Hettich, B.S. Freisen J. Am. Chem. Soc. 109, 3537 (1987)CrossRefGoogle Scholar
  34. 6.34
    R.L. Hettich, B.S. Freisen J. Am. Chem. Soc. 107, 6222 (1985)CrossRefGoogle Scholar
  35. 6.35
    R.L. Hettich, T.C. Jackson, E.M. Stanko, B.S. Freisen J. Am. Chem. Soc. 108, 5086 (1986)CrossRefGoogle Scholar
  36. 6.36
    P.R. Buseck, S.J. Tsipursky, R.L. Hettich: Science 257, 215 (1992)CrossRefADSGoogle Scholar
  37. 6.37
    T. Guo, C. Jin, R.E. Smalley: J. Phys. Chem. 95, 4948 (1991)CrossRefGoogle Scholar
  38. 6.38
    R.L. Hettich, R.N. Compton, R.H. Ritchie: Phys. Rev. Lett. 67, 1242 (1991)CrossRefADSGoogle Scholar
  39. 6.39
    P.A. Limbach, L. Schweikhard, K.A. Cowen, M.T. McDermott, A.G. Marshall, J.V. Coe: J. Am. Chem. Soc. 113, 6795 (1991)CrossRefGoogle Scholar
  40. 6.40
    J.A. Zimmerman, J.R. Eyler, S.B.H. Bach, S.W. McElvany: J. Chem. Phys. 94, 3556 (1991)CrossRefADSGoogle Scholar
  41. 6.41
    R.T. Laaksonen: Hydrogen chemisorption on transition metal clusters. Ph.D. Thesis, Rice University, Houston, TX (1991)Google Scholar
  42. 6.42
    M.A. Nygren, P.E.M. Siegbahn, C. Jin, T. Guo, R.E. Smalley: J. Chem. Phys. 95, 6181 (1991)CrossRefADSGoogle Scholar
  43. 6.43
    M. Karas, K. Bachmann, U. Bahr, F. Hillenkamp: Int J. Mass Spectrom. Ion Proc. 78, 53 (1987)CrossRefGoogle Scholar
  44. 6.44
    R.L. Hettich, M.V. Buchanan: J. Am. Soc. Mass Spectrom. 2, 22 (1991)CrossRefGoogle Scholar
  45. 6.45
    L.M. Nuwaysir, C.L. Wilkins: SPIE 1437, 112 (1991)CrossRefADSGoogle Scholar
  46. 6.46
    R.L. Hettich, M.V. Buchanan: J. Am. Soc. Mass Spectrom. 2, 402 (1991)CrossRefGoogle Scholar
  47. 6.47
    R.L. Hettich, M.V. Buchanan: Int. J. Mass Spectrom. Ion Phys. 111, 365 (1991)CrossRefADSGoogle Scholar
  48. 6.48
    C.B. Lebrilla, D.T.-S. Wang, R.L. Hunter, R.T. Mclver, Jr.: Anal. Chem. 62, 878 (1990)Google Scholar
  49. 6.49
    R.C. Beavis, B.T. Chait: Chem. Phys. Lett. 181, 479 (1991)CrossRefADSGoogle Scholar
  50. 6.50
    Y. Pan, R.J. Cotter: Org. Mass Spectrom. 27, 3 (1992)CrossRefGoogle Scholar
  51. 6.51
    T. Solouki, D.H. Russell: Proc. Natl. Acad. Sci. USA 89, 5701 (1992)CrossRefADSGoogle Scholar
  52. 6.52
    J.A. Castoro, C. Koster, C. Wilkins: Rapid Comm. Mass Spectrom. 6, 239 (1992)CrossRefGoogle Scholar
  53. 6.53
    C. Koster, J.A. Castoro, C.L. Wilkins: J. Am. Chem. Soc. 114, 7572 (1992)CrossRefGoogle Scholar
  54. 6.54
    J.A. Castoro, R.W. Chiu, C.A. Monnig, C.L. Wilkins: J. Am. Chem. Soc. 114, 7571 (1992)CrossRefGoogle Scholar
  55. 6.55
    J.C. Dunphy, K.L. Busch, R.L. Hettich, M.V. Buchanan: Anal. Chem. 65, 1329 (1993)CrossRefGoogle Scholar
  56. 6.56
    J.C. Dunphy, K.L. Busch, R.L. Hettich, M.V. Buchanan: unpublished resultsGoogle Scholar
  57. 6.57
    D.L. Rempel, R.P. Grese, M.L. Gross: Int. J. Mass. Spectrom. Ion Proc. 100, 381 (1990)CrossRefGoogle Scholar
  58. 6.58
    M.D.A. Mabud, M.J. Dekrey, R.G. Cooks: Int. J. Mass. Spectrom. Ion Proc. 67, 285 (1985)CrossRefGoogle Scholar
  59. 6.59
    E.R. Williams, K.D. Henry, F.W. McLafferty, J. Shabanowitz, D.F. Hunt: J. Am. Soc. Mass Spectrom. 1, 413 (1990)CrossRefGoogle Scholar
  60. 6.60
    J.A. Castoro, L.M. Nuwaysir, C.F. Ijames, C.L. Wilkins: Anal. Chem. 64, 2238 (1992)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • R. L. Hettich
  • C. Jin

There are no affiliations available

Personalised recommendations