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The Hairpin Elements of Nucleic Acid Structure: DNA and RNA Folding

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Book cover Nucleic Acids and Molecular Biology

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 8))

Abstract

Hairpin molecules have attracted a great deal of interest for many years. On one hand, this is because of their role in cellular processes, the recognition between the codon on mRNA and the anti-codon loop of tRNA being the most outstanding example. On the other hand, the study of the folding in hairpin loops and the thermodynamic parameters governing hairpin formation has been considered as a basis for the description of the stereochemistry of folding in more complicated nucleic acid structures and for the prediction of the secondary structure and its stability in such molecules.

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Authors and Affiliations

  1. NSR Center for Molecular Structure, Synthesis and Design. Laboratory of Biophysical Chemistry, University of Nijmegen, Toernooiveld, 6525 ED, Nijmegen, The Netherlands

    C. W. Hilbers, H. A. Heus, M. J. P. van Dongen & S. S. Wijmenga

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  1. C. W. Hilbers
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  2. H. A. Heus
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  3. M. J. P. van Dongen
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  4. S. S. Wijmenga
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Editors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Straße 3, 37075, Göttingen, Germany

    Fritz Eckstein

  2. Biochemistry Department, University of Dundee, Dundee, DD1 4HN, UK

    David M. J. Lilley

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© 1994 Springer-Verlag Berlin Heidelberg

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Hilbers, C.W., Heus, H.A., van Dongen, M.J.P., Wijmenga, S.S. (1994). The Hairpin Elements of Nucleic Acid Structure: DNA and RNA Folding. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78666-2_4

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