Abstract
Cholera is a disease which has been known for many centuries and is readily identified by description in even in the most ancient of writings. Typically, it has been associated with the Indian subcontinent, but has been able to cross the globe. Since the beginning of the nineteenth century, seven pandemics have spread in waves, facilitated by increased mobility of the human population. The etiological agent Vibrio cholerae was first described by Pacini in 1854 and subsequently rediscovered in 1883 by Koch, who demonstrated the causal relationship with the disease. (An excellent treatise on the history of cholera has recently been published; BARUA 1992)
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Manning, P.A. (1994). Surface-Associated and Soluble Components of Vibrio cholerae Involved in Bacteria-Host Interactions. In: Dangl, J.L. (eds) Bacterial Pathogenesis of Plants and Animals. Current Topics in Microbiology and Immunology, vol 192. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78624-2_12
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