The Role of Nephrectomy in Metastatic Renal Cell Carcinoma
Radical nephrectomy is well established as the standard treatment for localized renal cell carcinoma. Nephrectomy is the only known curative therapy for this tumor. The role of radical nephrectomy in the management of metastatic renal cell carcinoma is controversial and has come under increased scrutiny in the past several years with the development of immunotherapy, which has the potential to cure systemic renal cell carcinoma. Thus, immunotherapy combined with radical nephrectomy has the potential to cure patients with metastatic disease.
KeywordsRenal Cell Carcinoma Metastatic Renal Cell Carcinoma Radical Nephrectomy Spontaneous Regression Paraneoplastic Syndrome
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- 5.Frank J (1992) Nephrectomy in metastatic renal cell carcinoma. J Urol 147: 421AGoogle Scholar
- 8.deKernion JB, Ramming KD, Smith RB (1978) The natural history of metastatic renal cell carcinoma: a computer analysis. J Urol 120: 148Google Scholar
- 10.Bukowski R, Murthy S, Klein EA et al. Tumor infiltrating lymphocytes in metastatic renal cell carcinoma: the Cleveland clinic experience. In: Klein EA, Bukowski R, Finke J (eds) The immunobiology of renal cell carcinoma, (in press)Google Scholar
- 15.Fowler JE (1987) Urol Clin North Am 14: 745–756Google Scholar