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The Role of Cytotoxic T Lymphocytes in Infectious Disease: History, Criteria, and State of the Art

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Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 189))

Abstract

Observations made on children with genetic deficiencies of their immune system reveal that those lacking the capacity to make antibodies nevertheless handle most viral infections as well as normal individuals do. Such a- or hypogammaglobulinemic children are often susceptible to bacterial infections. Conversely, children with genetic deficiencies in their ability to mount cell-mediated immune responses or those who acquire diseases of lymphoid tissues later in life are often susceptible to a range of viral infections (reviewed in Good 1991; Riches 1992).

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Authors and Affiliations

  1. Viral Immunobiology Laboratory, Division of Virology, Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA, 92037, USA

    M. B. A. Oldstone

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  1. M. B. A. Oldstone
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Editors and Affiliations

  1. Department of Neuropharmacology Division of Virology, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, California, 92037, USA

    Michael B. A. Oldstone

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© 1994 Springer-Verlag Berlin Heidelberg

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Oldstone, M.B.A. (1994). The Role of Cytotoxic T Lymphocytes in Infectious Disease: History, Criteria, and State of the Art. In: Oldstone, M.B.A. (eds) Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections. Current Topics in Microbiology and Immunology, vol 189. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78530-6_1

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  • DOI: https://doi.org/10.1007/978-3-642-78530-6_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78532-0

  • Online ISBN: 978-3-642-78530-6

  • eBook Packages: Springer Book Archive

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