Clinical Relevance of Subclass Deficiency Diseases

  • L. Å. Hanson
  • M. Hahn-Zoric
  • V. Friman
  • K. Theman
  • J. Björkander
  • A. H. Lucas
  • A. T. Nagao


Patients with recurrent infections are common, but it is less common to find a diagnosis explaining the cause of their many infections. Immunodeficiencies are certainly valid as explanations, and the first discovered severe forms are relatively easy to recognize. The young infant with severe combined immunodeficiency or the adult with common variable immunodeficiency are diagnosed, but mainly by those who have learned to do so. Thus, the diagnostic delay for common variable immunodeficiency, which was 12 years in Sweden some 10 years ago (Björkander et al. 1985), is still 7 years, as a recent study in Norway performed by the Immunodeficiency Patient Group has shown (Brox 1993). For children born after 1980, the length of time before diagnosis was only 1 year, but for those born before 1965 it was 8 years.


Frequent Infection Common Variable Immunodeficiency Recurrent Otitis Medium Subclass Deficiency IgG2 Deficiency 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • L. Å. Hanson
  • M. Hahn-Zoric
  • V. Friman
  • K. Theman
  • J. Björkander
  • A. H. Lucas
  • A. T. Nagao

There are no affiliations available

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