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Antidepressiva in der Akutbehandlung depressiver Syndrome

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Alte und neue Medikamente in der psychiatrischen Therapie

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Zusammenfassung

Die vorrangige Indikation für eine Therapie mit Antidepressiva stellen depressive Syndrome unterschiedlichster Ätiologie dar. Während es sich jedoch für neuroleptische Behandlungen als sinnvoll erwiesen hat, klinische Indikationen an Zielsymtomen oder-Syndromen anstatt an nosologischen Klassifikationen auszurichten, wird diese Vorgehensweise für den klinischen Gebrauch der Antidepressiva immer wieder kontrovers diskutiert. So charakterisiert Kielholz (1972) zwar aufgrund klinischer Erfahrung die Antidepressiva nach ihrer bevorzugten Wirkung auf bestimmte Zielsymptome wie „psychomotorische Hemmung“, „vital depressive Verstimmung“ oder „psychomotorische Erregung“, kontrollierte klinische Studien können unterschiedliche therapeutische Profile der Antidepressiva bisher jedoch kaum bestätigen (Bielski u. Priedel 1976; Morris u. Beck 1974). Dabei ist jedoch durchaus in Betracht zu ziehen, daß die derzeitige klinisch-psychiatrische Methodologie und die bisher vorliegenden Studien vielleicht an sich vorhandene Unterschiede im Wirkprofil einzelner Antidepressiva nicht ausreichend darstellen können.

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Authors
  1. M. Schmauss
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Editors and Affiliations

  1. Psychiatrische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Nußbaumstraße 7, 80336, München, Deutschland

    Hanns Hippius  & D. Naber  & 

  2. Psychiatrische Klinik, Georg-August-Universität Göttingen, von-Siebold-Straße 5, 37075, Göttingen, Deutschland

    Eckart Rüther

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Schmauss, M. (1993). Antidepressiva in der Akutbehandlung depressiver Syndrome. In: Hippius, H., Naber, D., Rüther, E. (eds) Alte und neue Medikamente in der psychiatrischen Therapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78392-0_9

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  • DOI: https://doi.org/10.1007/978-3-642-78392-0_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57027-1

  • Online ISBN: 978-3-642-78392-0

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