Role of Nucleoside Diphosphate Kinase in G-Protein Action

  • N. Kimura
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 108 / 2)


Nucleoside diphosphate kinase (NDP kinase, EC is a ubiquitous enzyme which catalyzes a transfer of the terminal phosphate of 5′-triphosphate nucleotides to 5′-diphosphate nucleotides (Parks and Agarwal 1973). Under physiological conditions, NDP kinase works to form triphosphate nucleotide pools at the expense of ATP. The products of the enzyme reaction are widely utilized for syntheses of essential cellular compounds such as nucleic acids, proteins, polysaccharides, and lipids.


Adenylyl Cyclase Cholera Toxin Guanine Nucleotide Adenylyl Cyclase Activity Nucleoside Diphosphate Kinase 
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© Springer-Verlag Berlin Heidelberg 1993

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  • N. Kimura

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