Clinical Implications

  • Joachim Chrubasik
  • Sigrun Chrubasik
  • Laurence Mather

Abstract

To achieve effective epidural opioid analgesia, a critical mass or amount of opioid must be injected into the epidural space. A further increase in that dose does not materially shorten the onset time of analgesia. For example, the onset times of analgesia following epidural administration of 2, 4 or 8 mg morphine for management of pain after orthopedic surgery do not differ significantly. These doses also produce analgesia of equal quality. The quality of analgesia after epidural injection of 0.5 or 1 mg morphine, however, is significantly inferior (Martin et al. 1982).

Keywords

Epinephrine Diazepam Midazolam Paracetamol Rosen 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Joachim Chrubasik
    • 1
  • Sigrun Chrubasik
    • 2
  • Laurence Mather
    • 3
  1. 1.Department of AnesthesiologyUniversity HospitalHeidelbergGermany
  2. 2.Department of Forensic MedicineUniversity HospitalFreiburgGermany
  3. 3.Department of Anesthesia Royal North Shore HospitalUniversity of SydneySt. LeonardsAustralia

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