Ultraviolet-Induced Immune Suppression and its Relationship to Statospheric Ozone Depletion

  • E. C. De Fabo
  • F. P. Noonan
Conference paper
Part of the NATO ASI Series book series (volume 8)


Ultraviolet radiation-B (280–320nm) is linked directly to skin cancer formation and is also associated with significant immunological alterations leading to local and systemic immunosuppression in mammals. The mechanism as well as the short or long-term effects of such immunological perturbations is largely unknown. This mechanism may, however, play a critical role in human skin cancer development and other UVB-related disorders.


Stratum Corneum Immune Suppression Cutaneous Leishmaniasis Contact Hypersensitivity Systemic Immunosuppression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • E. C. De Fabo
    • 1
  • F. P. Noonan
    • 1
  1. 1.Department of DermatologyThe George Washington UniversityUSA

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