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How Many Ataxia-Telangiectasia Genes?

  • Conference paper
Ataxia-Telangiectasia

Part of the book series: NATO ASI Series ((ASIH,volume 77))

Abstract

In this chapter we review the evidence for genetic heterogeneity and clinical variability of A-T. Because of the existence of five complementation groups [Jasper et al. 1988], a homogeneity model is automatically suspect. There are also clinical variants of A-T, and those are discussed briefly.

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Author information

Authors and Affiliations

  1. Department of Pathology School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90024, USA

    Ethan Lange & Richard A. Gatti

  2. Department of Mathematics, University of California, Los Angeles, Los Angeles, CA, 90024, USA

    Ethan Lange

  3. Department of Biomathematics School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90024, USA

    Eric Sobel & Kenneth Lange

  4. The Virginia Mason Research Center, Seattle, WA, 98101, USA

    Patrick Concannon

Authors
  1. Ethan Lange
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  2. Richard A. Gatti
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  3. Eric Sobel
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  4. Patrick Concannon
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  5. Kenneth Lange
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Editor information

Editors and Affiliations

  1. Department of Pathology, University of California Los Angeles School of Medicine, Los Angeles, CA, 90024-6975, USA

    Richard A. Gatti

  2. Laboratory of Radiobiology and Environmental Health, University of California San Francisco, San Francisco, CA, 94143-0750, USA

    Robert B. Painter

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© 1993 Springer-Verlag Berlin Heidelberg

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Lange, E., Gatti, R.A., Sobel, E., Concannon, P., Lange, K. (1993). How Many Ataxia-Telangiectasia Genes?. In: Gatti, R.A., Painter, R.B. (eds) Ataxia-Telangiectasia. NATO ASI Series, vol 77. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78278-7_4

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  • DOI: https://doi.org/10.1007/978-3-642-78278-7_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78280-0

  • Online ISBN: 978-3-642-78278-7

  • eBook Packages: Springer Book Archive

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