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Mammography Screening for A-T Heterozygotes

  • Amos Norman
  • H. Rodney Withers
Part of the NATO ASI Series book series (volume 77)

Abstract

Swift et al (1992) have shown an increased incidence of breast cancer among A-T heterozygotes who had X-ray examinations five or more years prior to the diagnosis of the disease as compared to the incidence in the A-T heterozygotes who had not received such examinations. They assumed that the examinations were the cause for the increased incidence and suggested, therefore, that mammography screening may not be beneficial for A-T heterozygotes. We emphatically disagree: mammography screening is particularly beneficial for A-T heterozygotes whose risk for breast cancer is higher than for the general population.

Keywords

Breast Cancer Mammography Screening Natural Background Radiation Cellular Radiosensitivity Background Radiation Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Cole J, Arlett CF, Green, MH et al (1988) Comparative human cellular radiosensitivity. II. The survival following gamma irradiation of unstimulated (Go) T-lymphocytes, T-lymphocyte lines, lympho-blastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes. Int J Radiat Biol 54: 929–943PubMedCrossRefGoogle Scholar
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Amos Norman
    • 1
  • H. Rodney Withers
    • 1
  1. 1.Department of Radiation Oncology and Jonsson Comprehensive Cancer CenterUCLA Medical CenterLos AngelesUSA

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