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Basic and Clinical Aspects of Helicobacter pylori Infection pp 223–226Cite as

The Cloning and Partial Sequence Analysis of the Catalase Gene of Helicobacter pylori

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Abstract

Helicobacter pylori expresses significant quantities of a catalase, which may be an important virulence factor, modifying the effectiveness of the host polymorphonuclear cell responses to the organism at the gastric mucosal surface. Little is known about the structure of this enzyme. Hazell et al. [2] have shown that the native catalase is a structure is a tetramer with polypeptide subunits of 50 kDa. In addition, from other catalases it must also be assumed that is a metalloprotein containing a variable number of iron atoms.

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References

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Author information

Authors and Affiliations

  1. Central Veterinary Laboratory, Weybridge, UK

    D. G. Newell

  2. Institute for Infectious Diseases and Immunology, University of Utrecht, The Netherlands

    P. J. M. Nuijten

  3. Centre for Applied Microbiology and Research Porton Down, PHLS, Salisbury, SP4 OJG, UK

    D. G. Newell & A. R. Stacey

  4. School of Microbiology, University of New South Wales, Australia

    S. L. Hazell

Authors
  1. D. G. Newell
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  2. P. J. M. Nuijten
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  3. A. R. Stacey
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  4. S. L. Hazell
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Editor information

Editors and Affiliations

  1. I. Patologia Medica, Policlinico S. Orsola, Via Massarenti 9, I-40138, Bologna, Italy

    G. Gasbarrini  & S. Pretolani  & 

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© 1994 Springer-Verlag Berlin Heidelberg

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Cite this paper

Newell, D.G., Nuijten, P.J.M., Stacey, A.R., Hazell, S.L. (1994). The Cloning and Partial Sequence Analysis of the Catalase Gene of Helicobacter pylori . In: Gasbarrini, G., Pretolani, S. (eds) Basic and Clinical Aspects of Helicobacter pylori Infection. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78231-2_42

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  • DOI: https://doi.org/10.1007/978-3-642-78231-2_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78233-6

  • Online ISBN: 978-3-642-78231-2

  • eBook Packages: Springer Book Archive

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