Abstract
Helicobacter pylori (HP) strains differ considerably in their virulence characteristics. Only certains organisms, for example, produce a toxic substance which causes intracytoplasmic vacuolization on cells in vitro [2, 3]. Cytotoxic HP strains (CTHP) can also be considered ulcerogenic because they have been isolated with greater frequency from patients with peptic ulcers than from patients with chronic gastritis only [2]. Thus the vacuolating toxin most probably plays a crucial role in the pathogenic mechanism of the gastric mucosa damage.
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References
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© 1994 Springer-Verlag Berlin Heidelberg
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Figura, N. et al. (1994). Demonstration of the Major Cytotoxin-Associated Protein of Helicobacter pylori in Gastric Biopsies by Western Blotting. In: Gasbarrini, G., Pretolani, S. (eds) Basic and Clinical Aspects of Helicobacter pylori Infection. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78231-2_22
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DOI: https://doi.org/10.1007/978-3-642-78231-2_22
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