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The Role of Helicobacter pylori Gastritis in Ulcerogenesis and Carcinogenesis

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Basic and Clinical Aspects of Helicobacter pylori Infection

Abstract

Recent studies suggest that Helicobacter pylori (HP) gastritis is a major risk factor for both peptic ulcer disease [36] and cancer [16, 31, 32]. However, the histologic factors and mechanisms leading from gastritis to ulcer or cancer are poorly known. Gastritis activity and HP-linked surface epithelium lesions have been suggested to play some role in ulcerogenesis [7, 9, 12, 13, 15, 34] while intestinal metaplasia (IM) has long been indicated as a factor in cancerogenesis [6, 21, 22].

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Authors and Affiliations

  1. Department of Pathology, University of Pavia, Italy

    E. Solcia & R. Fiocca

  2. Pathology Service, IRCCS Policlinico San Matteo, 27100, Pavia, Italy

    E. Solcia, L. Villani, O. Luinetti & A. Gianatti

  3. Digestive Physiopathology Center, IRCCS Policlinico San Matteo, 27100, Pavia, Italy

    E. Trespi

  4. Pathology Service, General Hospital, Voghera, Italy

    G. Stella

  5. Pathology Service, General Hospital, Varese, Italy

    M. Cornaggia, A. Chiaravalli & C. Capella

  6. Department of Pathology, University of Pavia, Varese, Italy

    C. Capella

Authors
  1. E. Solcia
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  2. R. Fiocca
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  3. L. Villani
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  4. O. Luinetti
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  5. A. Gianatti
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  6. E. Trespi
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  7. G. Stella
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Editors and Affiliations

  1. I. Patologia Medica, Policlinico S. Orsola, Via Massarenti 9, I-40138, Bologna, Italy

    G. Gasbarrini  & S. Pretolani  & 

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© 1994 Springer-Verlag Berlin Heidelberg

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Solcia, E. et al. (1994). The Role of Helicobacter pylori Gastritis in Ulcerogenesis and Carcinogenesis. In: Gasbarrini, G., Pretolani, S. (eds) Basic and Clinical Aspects of Helicobacter pylori Infection. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78231-2_20

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  • DOI: https://doi.org/10.1007/978-3-642-78231-2_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78233-6

  • Online ISBN: 978-3-642-78231-2

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