Haemagglutinins of Helicobacter pylori and Adherence to HEp-2 Cells
Adherence to surface receptors is an essential step in pathogenesis for many bacteria. Attachment is mediated by adhesions or ligands which may be soluble or cell-associated, and which can be demonstrated by haemagglutination of various species of erythrocyte. Mannose-resistant haemagglutination by H. pylori has been described by Evans et al.  and others [2, 4]. However, these reports disagree on the properties of the haemagglutinins. Furthermore, different workers have used different methods of testing for HA; Evans et al. used slide haemagglutination , but Huang et al. used a micro-titre method . It is probable that some of these differences are explained by the presence of different adhesins so that more than one type of receptor is involved.
KeywordsSialic Acid Haemagglutinating Activity Bovine Submaxillary Mucin Colonization Factor Antigen Stomach Antrum
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