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Growth Hormone and Somatomedins during Lifespan pp 329–335Cite as

Long-term Growth Hormone Therapy in Adulthood: Potential Risk and Benefits

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Abstract

The realization of the physiological role of growth hormone (GH) during adulthood and the availability of large amounts of recombinant GH have resulted in a rapidly increasing number of clinical studies to answer three questions:

  1. 1.

    Do GH-deficient adults benefit from long-term GH supplementation in a dose which mimics “normal” GH secretion?

  2. 2.

    Is it possible to influence and/or delay normal ageing by the long-term use of GH and how safe will this be?

  3. 3.

    Is it possible and worthwhile to try to overcome the often major catabolic effects of severe illnesses by short-term administration of pharmacological amounts of GH?

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Authors
  1. S. W. J. Lamberts
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  2. A. Binnerts
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, School of Medicine, University of Milan, Via Vanvitelli 32, 20129, Milan, Italy

    Eugenio E. Müller (Professor of Pharmacology) & Vittorio Locatelli (Associate Professor of Pharmacology) (Professor of Pharmacology) &  (Associate Professor of Pharmacology)

  2. Pharmaco-biological Institute, University of Bari, 70125, Bari, Italy

    Daniela Cocchi (Professor of Pharmacology) (Professor of Pharmacology)

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© 1993 Springer-Verlag Berlin Heidelberg

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Lamberts, S.W.J., Binnerts, A. (1993). Long-term Growth Hormone Therapy in Adulthood: Potential Risk and Benefits. In: Müller, E.E., Cocchi, D., Locatelli, V. (eds) Growth Hormone and Somatomedins during Lifespan. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78217-6_28

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  • DOI: https://doi.org/10.1007/978-3-642-78217-6_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78219-0

  • Online ISBN: 978-3-642-78217-6

  • eBook Packages: Springer Book Archive

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