Skeletal Growth: A New Parameter in the Evaluation of Experimental Arthritis

  • E. del Pozo
Conference paper

Abstract

Previous observations have revealed that, in children with arthritis of different etiologies, growth retardation and osteopenia are common findings (Ansell and Kent 1977; White 1990 Truckenbrodt and Hafner 1991). The condition may vary in accordance with periods of exacerbation, showing growth delay, and a catch-up phenomenon recorded during remission. This pathology improves with specific antiarthritic therapy.

Keywords

Arthritis Paraffin Cyclosporin Rheumatol 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aitman TJ, Palmer RJ, Loftus J, Ansell BM, Royston JP, Teale JD, Clayton RN (1989) Serum IGF-1 levels and growth failure in juvenile chronic arthritis. Clin Exp Rheumatol 7:557–561.PubMedGoogle Scholar
  2. Ansell BM, Beiwaters EGL (1956) Growth in Still’s disease. Ann Rheum Dis 15:295–319.PubMedCrossRefGoogle Scholar
  3. Ansell BM, Kent PA (1977) Radiological changes in juvenile chronic polyarthritis. Skeletal Radiol 1:129–144.CrossRefGoogle Scholar
  4. Bennet AE, Silverman ED, Miller JJ, Hintz RL (1988) Insulin-like growth factors I and II in children with systemic onset juvenile arthritis. J Rheumatol 15:655–658.Google Scholar
  5. del Pozo E, Gubler HU, Perrelet R, Hager T, Wiederhold KH (1988) Non-invasive quantitative estimation of bone density in rats throughout life cycle and in arthritic osteopenia: preliminary results. Horm Metab Res 20:630–632.PubMedCrossRefGoogle Scholar
  6. del Pozo E, Graeber M, Elford P, Payne T (1990) Regression of bone and cartilage loss in adjuvant arthritic rats after treatment with cyclosporin A. Arthritis Rheum 33:247–252.PubMedCrossRefGoogle Scholar
  7. del Pozo E, Elford P, Perrelet R, Graeber M, Casez JP, Modrowski D, Payne T, MacKenzie A (1992) Prevention of adjuvant arthritis by cyclosporine in rats. Semin Arthritis Rheum 21[Suppl 3]:23–29.PubMedCrossRefGoogle Scholar
  8. Miller ML, Chocko JA, Young EA (1989) Dietary deficiencies in children with rheumatoid arthritis. Arthritis Care Res 2:22–24.PubMedCrossRefGoogle Scholar
  9. Mortensen AL, Allen JR, Allen RC (1990) Nutritional assessment of children with juvenile chronic arthritis. J Paediatr Child Health 26:335–338.PubMedCrossRefGoogle Scholar
  10. Svantesson H (1991) Treatment of growth failure with human growth hormone in patients with juvenile chronic arthritis. A pilot study. Clin Exper Rheumatol 9[Suppl 6]:47–50.Google Scholar
  11. Truckenbrodt H, Hafner R (1991) Allgemeine und lokale Wachstumsstörungen bei chronischer Arthritis im Kindesalter. Schweiz Med Wochenschr 121:608–620.PubMedGoogle Scholar
  12. White PH (1990) Growth abnormalities in children with rheumatoid arthritis. Clin Orthop 259:46–50.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • E. del Pozo

There are no affiliations available

Personalised recommendations