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Micronucleus Assays

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Advances in Mutagenesis Research

Part of the book series: Advances in Mutagenesis Research ((MUTAGENESIS,volume 5))

Abstract

Small, round-shaped structures that stained like the cell nucleus were observed in the cytoplasm of erythrocytes more than a century ago (Neumann 1869, p. 78; Howell 1891; for a review of the early literature see Jolly 1907, in particular pp. 207–224). These structures, called “fragment of nuclear material” by Howell or “corpuscules intraglobulaires” in the termination of Jolly, are known to the hematologist as “Howell-Jolly bodies”.

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  1. Institut für Medizinische Strahlenbiologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Germany

    W.-U. Müller & C. Streffer

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  1. W.-U. Müller
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    Günter Obe

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Müller, WU., Streffer, C. (1994). Micronucleus Assays. In: Obe, G. (eds) Advances in Mutagenesis Research. Advances in Mutagenesis Research, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78193-3_1

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