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Micronucleus Assays

  • W.-U. Müller
  • C. Streffer
Part of the Advances in Mutagenesis Research book series (MUTAGENESIS, volume 5)

Abstract

Small, round-shaped structures that stained like the cell nucleus were observed in the cytoplasm of erythrocytes more than a century ago (Neumann 1869, p. 78; Howell 1891; for a review of the early literature see Jolly 1907, in particular pp. 207–224). These structures, called “fragment of nuclear material” by Howell or “corpuscules intraglobulaires” in the termination of Jolly, are known to the hematologist as “Howell-Jolly bodies”.

Keywords

Chromosome Aberration Micronucleus Test Micronucleus Assay Chinese Hamster Cell Micronucleus Frequency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • W.-U. Müller
    • 1
  • C. Streffer
    • 1
  1. 1.Institut für Medizinische StrahlenbiologieUniversitätsklinikum EssenEssenGermany

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