Rational Long-Term Therapy of Peptic Ulcer Disease
Peptic ulcer is a chronic disease characterized by spontaneous remissions and relapses which may lead to potentially lethal complications such as hemorrhage and perforation. The duration of this relapsing tendency is unpredictable in any individual patient but may last for many years, if not the entire lifetime, thus making a long-term treatment strategy a necessity. In recent years, various therapeutic opinions to maintain the disease in remission have become available, each one with a number of advantages and disadvantages. The present paper aims to review the different therapeutic options for the long-term management of peptic ulcer disease, with particular reference to their ability to prevent recurrences and complications.
KeywordsPlacebo Prostaglandin Bismuth Perforation Tetracycline
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