Acidosis: A Marker for Penumbra or a Target for Treatment?
The recognition that lactate and proton accumulation in the ischaemic brain develop at relatively superficial levels of ischaemia has prompted several lines of investigation in recent years. Two examples are discussed in this chapter, one in the area of basic pathophysiology of focal ischaemia and the second in that of therapy.
KeywordsMiddle Cerebral Artery Occlusion Spreading Depression Cereb Blood Flow Extracellular Potassium Potassium Depletion
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