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Phenylalkylamine Calcium Antagonists as Cerebroprotective Agents

  • Conference paper
Cerebral Ischemia and Basic Mechanisms

Abstract

Ion channels which are selectively permeable to Ca2+ and regulated primarily by changes in membrane potential are present in virtually every excitable cell. The physiological role and pharmacological relevance of these voltage-sensitive Ca2+ channels was first recognized in the heart, where they were shown to be the site of action of cardiodepressant drugs described functionally as calcium antagonists.

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Author information

Authors and Affiliations

  1. Department of Neuropharmacology, Knoll AG, 67061, Ludwigshafen, Germany

    L. Szabo, H. P. Hofmann & L. Unger

Authors
  1. L. Szabo
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  2. H. P. Hofmann
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  3. L. Unger
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Editor information

Editors and Affiliations

  1. Neurologische Universitätsklinik, Sigmund-Freud-Straße 25, 53127, Bonn, Germany

    Alexander Hartmann

  2. Department of Neurology, Texas Medical Center, The University of Texas, 6431 Fannin, Suite 7.004 MSB, 77030, Houston, TX, USA

    Frank Yatsu

  3. Institut für Physiologie, Universität Heidelberg, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany

    Wolfgang Kuschinsky

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© 1994 Springer-Verlag Berlin Heidelberg

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Szabo, L., Hofmann, H.P., Unger, L. (1994). Phenylalkylamine Calcium Antagonists as Cerebroprotective Agents. In: Hartmann, A., Yatsu, F., Kuschinsky, W. (eds) Cerebral Ischemia and Basic Mechanisms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78151-3_17

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  • DOI: https://doi.org/10.1007/978-3-642-78151-3_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78153-7

  • Online ISBN: 978-3-642-78151-3

  • eBook Packages: Springer Book Archive

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