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Die Antibiotika-imprägnierte Spongiosaplastik als biologische Trägersubstanz in der Osteomyelitis-Behandlung

  • K. Neumann
  • W. Buchholz
  • G. Muhr
Conference paper
Part of the Langenbecks Archiv für Chirurgie book series (DTGESCHIR, volume 1993)

Antibiotic Impregnated Spongiosaplasty as Biologic Carrier Substance in Treatment of Osteomyelitis

Summary

Bacterial adhesion and its ability to elaborate a protective exopolysaccharide biofilm is a critical factor in pathogenesis of chronic osteomyelitis. Repetitive radical debridement to viable and well perfused cortical bone — controlled by scintigram and antibiogram — together with vancomycin- and tobramycin-impregnated cancellous grafts induce a permanent revascularization of the defect (biointegration).

Key words

Chronic osteomyelitis Bacterial adhesion Antibiotic impregnated bone graft 

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Literatur

  1. 1.
    Cierny G, Mader JT, Penninck JJ (1980) A clinical staging system for adult osteomyelitis. Cont Orthop 10:5Google Scholar
  2. 2.
    Duwelius PJ, Schmidt AH (1992) Assessment of bone viability in patients with osteomyelitis: preliminary clinical experience with Laser Doppler Flowmetry. J Orthop Trauma 6:327PubMedCrossRefGoogle Scholar
  3. 3.
    Lindsey RW, Probe RS, Miclau T, Perren SM (1991) The effects of tobramycin impregnated on the incorporation of autologous cancellous bone graft. 6. Deutsch-Österreich-Schweizerische Unfalltagung 21.–25. 5.1991, WienGoogle Scholar
  4. 4.
    Wernet E, Ekkernkamp A, Jellestad H, Muhr G (1992) Antibiotikahaltiges Kollagenvlies in der Osteitistherapie. Unfallchirurg 95:259PubMedGoogle Scholar
  5. 5.
    Wood MB, Cooney WP, Irons GB (1985) Skeletal reconstruction by vascularized bone transfer: indications and results. Mayo Clin Proc 60:729PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • K. Neumann
    • 1
  • W. Buchholz
    • 1
  • G. Muhr
    • 1
  1. 1.Abteilung für Unfall- und WiederherstellungschirurgieKreiskrankenhaus — Akademisches Lehrkrankenhaus der Technischen Universität MünchenGarmisch-PartenkirchenDeutschland

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