Abstract
Dramatic improvement of clinical symptoms and signs is not infrequent in patients with acute ischemic stroke. Such a syndrome has been called the “spectacular shrinking deficit,” and its mechanism is presumed to be the rapid migration of an embolus to the distal branches of a cerebral artery after initially lodging in the main trunk [6, 7]. Supporting evidence for the mechanism and the frequency of this phenomenon has recently been reported by Minematsu and coworkers [5]. The existence of such patients encouraged us to carry out a clinical trial of thrombolytic therapy in acute ischemic stroke prior to the appearance of ischemic findings on computed tomography (CT).
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© 1993 Springer-Verlag Berlin Heidelberg
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Yamaguchi, T., Hayakawa, T., Kikuchi, H. (1993). Intravenous Tissue Plasminogen Activator in Acute Thromboembolic Stroke: A Placebo-Controlled, Double-Blind Trial. In: del Zoppo, G.J., Mori, E., Hacke, W. (eds) Thrombolytic Therapy in Acute Ischemic Stroke II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78061-5_9
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DOI: https://doi.org/10.1007/978-3-642-78061-5_9
Publisher Name: Springer, Berlin, Heidelberg
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