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Acute Central Retinal Artery Occlusion and the Role of Thrombolysis

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Thrombolytic Therapy in Acute Ischemic Stroke II

Abstract

Central retinal artery occlusion (CRAO) is one of the major causes for monocular blindness in the elderly. The diagnosis is easily achievable by means of clinical signs and symptoms and ophthalmoscopy. Spontaneous improvement is a rare event and treatments using vasoactive drugs are poorly effective. Up to now fibrinolysis seems to be the only rational treatment for CRAO. In 1992 Schmidt and colleagues [1] reported on successful treatments of CRAO employing superselective microcatheter techniques with local application of urokinase into the ophthalmic artery. The most surprising result was the observation that vision may recover even more than 6 h after retinal stroke.

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References

  1. Schmidt D, Schumacher M, Wakhloo AK (1992) Catheter fibrinolytic therapy with urokinase in central retinal artery occlusion. Am J Ophthalmol (In Press)

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  2. Zeumer H, Freitag HJ, Knospe V (1992) Intravascular thrombolysis in CNS cerebrovascular disease. Neuroimaging (In Press)

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  3. Zeumer H, Freitag HJ, Zanella F, et al (1992) Local intra-arterial fibrinolytic therapy in stroke patients: Urokinase versus rtPA. Neuroradiology (UnPub)

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© 1993 Springer-Verlag Berlin Heidelberg

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Freitag, HJ., Zeumer, H., Knospe, V. (1993). Acute Central Retinal Artery Occlusion and the Role of Thrombolysis. In: del Zoppo, G.J., Mori, E., Hacke, W. (eds) Thrombolytic Therapy in Acute Ischemic Stroke II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78061-5_15

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  • DOI: https://doi.org/10.1007/978-3-642-78061-5_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56442-3

  • Online ISBN: 978-3-642-78061-5

  • eBook Packages: Springer Book Archive

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