Zusammenfassung
Die Indikationen für eine Psychopharmakotherapie im Kindes- und Jugendalter sind begrenzt. Dies hat seinen Grund in der Tatsache, daß das junge Individuum sich in einer Periode der Reifung und Entwicklung befindet. Die Interaktionen zwischen Pharmaka und Stoffwechsel sind daher komplexer und weniger übersichtlich als bei Erwachsenen.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Aman MG, Turbott SH (1991) Prediction of clinical response in children taking methylphenidate. J Autism Dev Disord 21: 211–228
Baldessarini RJ, Conners CK, Eisenberg L (1972) Symposium: Behaviour modification by drugs. Pediatrics 49/5: 694–715
Balthazor MJ, Wagner RK, Pelham WE (1991) The specificity of the effects of stimulant medication on classroom learning-related measures of cognitive processing for attention deficit disorder children. J Abnorm Child Psychol 19: 35–52
Barkley RA (1977) A review of stimulant drug research with hyperacitve children. J Child Psychol Psychiatry 18: 137–165
Barkley RA, Anastopoulos AD, Guevremont DC, Fletcher KE (1991) Adolescents with ADHD: Patterns of behavioral adjustment, academic functioning, and treatment utilization. J Am Acad Child Adolesc Psychiatry 30: 752–761
Barrickman L, Noyes R, Kuperman S, Schumacher E, Verda M (1991) Treatment of ADHD with Fluoxetine: A preliminary trial. J Am Acad Child Adolesc Psychiatry 5: 762–767
Biederman J, Baldessarini RH, Wright V, Knee D, Harmatz JS (1989) A double-blind placebo controlled study of desipramine in the treatment of ADD: I. efficacy. J Am Acad Child Adolesc Psychiatry 28: 777–784
Bradley C (1937) The behavior of children receiving benzedrine. Am J Psychiatry 94: 577–585
Brown RT, Jaffe SL, Silverstein J, Magee H (1991) Methylphenidate and adolescents hospitalized with conduct disorder: Dose effects on classroom behavior, academic performance, and impulsivity. J Clin Child Psychol 3: 282–292
Carlson CL, Pelham WE, Swanson JM, Wagner JL (1991) A divided attention analysis of the effects of methylphenidate on the arithmetic performance of children with attention-deficit hyperactivity disorder. J Child Psychol Psychiatry 32: 463–471
Carlsson A (1980) Psychopharmacology: Basic aspects. In: Kisker KP, Meyer JE, Müller C, Strömgren E (Hrsg) Psychiatrie der Gegenwart, Bd I/2, 2. Aufl. Springer, Berlin Heidelberg New York, S 197–242
Coons HW, Klorman R, Borgstedt A (1987) Effects of methylphenidate on adolescents with a childhood history of attention deficit disorder: II. Information Processing. J Am Acad Child Adolesc Psychiatry 26: 368–374
Coyle JT (1976) Neurochemical aspects of the development of the dopaminergic innervation of the striatum. In: Brazier MAB, Coceani F (eds) Brain dysfunction in infantile febrile convulsions. Raven Press, New York, pp 25–39
Cunningham CE, Siegel LS, Offord DR (1991) A dose-response analysis of the effects of methylphenidate on the peer interactions and simulated classroom performance of ADD children with and without conduct problems. J Child Psychol Psychiatry 32: 439–452
Donnelly M, Zametkin AZ, Rapoport JL et al. (1986) Treatment of childhood hyperactivity with desipramine: Plasma drug concentration, cardiovascular effects, plasma and urinary catecholamine levels, and clinical response. Clin Pharmacol Ther 39: 72–81
Douglas VI, Barr RG, Amin K, O’Neill ME, Britton BG (1988) Dosage effects and individual responsivity to methylphenidate in attention deficit disorder. J Child Psychol Psychiatry 29: 453–475
Dyck LE, Boulton AA, Jones RS (1980) A comparison of the effects of methylphenidate and amphetamine on the simultaneous release of radio-labelled dopamine and p- or m-tyramine from rat striatal slices. Eur J Pharmacol 68: 33
Dykmann RA, Ackermann PT, McCray DS (1980) Effects of methylphenidate on selective and sustained attention in hyperactive reading-disabled and presumably attention-disordered boys. J Nerv Ment Dis 168: 745–752
Eggers C (1984) Sozialisationsstörungen (Aggressivität, Autoaggressivität). In: Nissen G, Eggers C, Martinius J (Hrsg) Kinder- und jugendpsychiatrische Pharmakotherapie. Springer, Berlin Heidelberg New York Tokyo, S 313–316
Evans SW, Pelham E (1991) Psychostimulant effects on academic and behavioral measures for ADHD junior high school students in a lecture format classroom. J Abnorm Child Psychol 19: 537–552
Ferris RM, Tang FL, Maxwell RA (1972) A comparison of the capacities of isomers of amphetamine, deoxypipradol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptomosol preparations of rat cerebral cortex, hypothalamus and striatum into adrenergic nerves of rabbit aorta. J Pharmacol Exp her 181: 407–416
Gibbs CJ, Bolis CL (1991) NINS New issues in neurosciences. Basic and clinical approaches, vol 3/1. Thieme, Stuttgart, pp 75–78
Golinko BE, Rennick PM, Lewis RF (1981) Predicting stimulant effectiveness in hyperactive children with a repeatable neuropsychological battery. Prog Neuropsychopharmacol 5: 65–68
Gualtieri CT (1991) Neuropsychiatry and behavioral pharmacology. Springer, Berlin Heidelberg New York Tokyo
Gualtieri CT, Hicks RE (1986) Neuropharmacology of methylphenidate and a neural substrate for childhood hyperactivity. Psychiatr Clin North Am 8: 875–892
Gualtieri CT, Keenan PA, Chandler M (1991) Clinical and neuropsychological effects of desipramine in children with attention deficit hyperactivity disorder. J Clin Psychopharmacol 11: 155–159
Hechtmann L, Weiss G, Perlman T (1984) Young adult outcome of hyperactive children who received long-term stimulant treatment. J Am Acad Child Adolesc Psychiatry 23: 261–269
Hinshaw SP (1987) On the distinction between attentional deficits/hyperactivity and conduct problems/aggression in child psychopathology. Psychol Bull 101: 443–463
Hinshaw SP (1991) Stimulant medication and the treatment of aggression in children with attentional deficits. J Clin Child Psychol 20: 301–312
Homann HD, Ziance RJ (1981) The effects of d-amphetamine and potassium on serotonin release and metabolism in rat cerebral cortex tissue. Res Commun Chem Pathol Pharmacol 31: 223
Horn WF, Ialongo NS, Pascoe JM et al. (1991) Additive zeffects of psychostimulants, parent training, and self-control therapy with ADHD children. J Am Acad Child Adolesc Psychiatry 30: 233–240
Jacobvitz D, Sroufe LA, Stewart M, Leffert N (1990) Treatment of attentional and hyperactivity problems in children with sympathomimetic drugs: A comprehensive review. J Am Acad Child Adolesc Psychiatry 29: 677–688
Just MA, Carpenter PA (1980) A theory of reading: From eye fixations to comprehension. Psychol Rev 87: 329–354
Kaplan SL, Busner J, Kupietz S, Wassermann E, Segal B (1990) Effects of methylphenidate on adolescents with aggressive conduct disorder and ADHD: A preliminary report. J Am Acad Child Adolesc Psychiatry 29: 719–723
Kaye DB (1986) The development of mathematical cognition. Cogn Dev 1: 157–170
Klorman R, Brumaghim JT, Fitzpatrick PA, Borgstedt AD (1990) Clinical effects of a controlled trial of methylphenidate on adolescents with attention deficit disorder. J Am Acad Child Adolesc Psychiatry 29: 702–709
Lambert NM (1988) Adolescent outcomes for hyperactive children: perspectives on general and specific patterns of childhood risk for adolescent educational, social and mental health problems. Am J Psychol 43: 786–799
Langee HR (1989) A retrospective study of mentally retarded patients with behavior disorders who were treated with carbamazepine. Am J Ment Retard 93: 640–643
Mannuzza S, Gittlemann-Klein R, Bonagura N, Horowitz-Konig P, Shenker R (1988) Hyperactive boys almost grown up. Arch Gen Psychiatry 45: 13–18
McBride MC (1988) An individual double-blind crossover trial for assessing methylphenidate response in children with attention deficit disorder. J Pediatr 113: 137
Rapport MD, Stoner G, DuPaul GJ, Kelly KL, Tucker SB, Schoeler T (1988) Attention deficit disorder and methylphenidate: A multilevel analysis of dose-response effects on children’s impulsivity accross settings. J Am Acad Child Adolesc Psychiatry 27: 60–69
Reid AH, Naylor GT, Kay DSG (1981) A double blind placebo controlled crossover trial of carbamazepine in overactive severely mentally handicapped patients. Psychol Med 11: 109–113
Riddle MA, Hardin MT, Cho SC, Wollston JL, Leckman JF (1988) Desipramine treatment of boys with attention-deficit hyperacitivity disorder and tics: preliminary clinical experience. J Am Child Adolesc Psychiatry 27: 811–814
Ross SB (1978) Antagonism by methylphenidate of the stereotyped behavior produced by (+)-amphetamine in reserpinized rats. J Pharm Pharmacol 30: 253–254
Schachar R, Taylor E, Wieselberg M, Thorley G, Rutter M (1987) Changes in family function and relationship in children who respond to methylphenidate. J Am Acad Child Adolesc Psychiatry 26: 728–732
Shaywitz SE, Shaywitz BA (1984) Diagnosis and management of attention deficit disorder. A pediatric perspective. Pediatr Clin North Am 31: 429
Solanto MV (1984) Neuropharmacological basis of stimulant drug action in attention deficit disorder with hyperactivity: A review and synthesis. Psychol Bull 95: 387–409
Sonneville de LMJ, Njiokiktjien C, Hilhorst RC (1991) Methylphenidate-induced changes in ADHD information processors. J Child Psychol Psychiatry 32: 285–295
Stevenson RD, Wolraich ML (1989) Stimulant medication therapy in the treatment of children with attention deficit hyperactivity disorder. Clin Pharmacol 36: 1183–1197
Tannock R, Schachar RJ, Carr RP, Chajczyk D, Logan GD (1989) Effects of methylphenidate on inhibitory control in hyperactive children. J Abnorm Child Psychol 17: 473–491
Weingartner H, Rapoport JL, Buchsbaum MS, Bunney Jr WE, Ebert MH, Mikkelsen EJ, Caine ED (1980) Cognitive processes in normal and hyperactive children and their response to amphetamine treatment. J Abnorm Psychol 89: 25–37
Weiss G, Hechtman LT (1986) Hyperactive children grown up. Guilford, New York
Weiss G, Kruger E, Davidson V, Elman J (1975) Effects of longterm treatment of hyperactive children with methylphenidate. Can Med Assoc J 112: 159–165
Wright FS (1982) Learning disabilities and associated conditions. General considerations and approach to learning disabilities. In: Swaimann KF, Wright FS (eds) The practice of pediatric neurology. Mosby, St. Louis
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Eggers, C. (1993). Behandlung von Kindern mit Psychopharmaka unter Berücksichtigung frühkindlicher Hirnschäden. In: Möller, HJ., Przuntek, H. (eds) Therapie im Grenzgebiet von Psychiatrie und Neurologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78040-0_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-78040-0_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-56399-0
Online ISBN: 978-3-642-78040-0
eBook Packages: Springer Book Archive