Hyperparathyroid and Hypoparathyroid Bone Disease

  • M. Peacock
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 107)


Hyperparathyroid and hypoparathyroid diseases provide unique insights into the action of parathyroid hormone (PTH) on bone. Diseases of excess PTH arise either as a primary abnormality in hormone secretion, or as a compensatory response to a disorder of serum calcium homeostasis. Hypoparathyroidism usually arises from surgical removal of the parathyroids, although it may arise as an idiopathic disease. Uncommonly, the parathyroid receptor is defective, giving rise to increased PTH secretion but with failure of biological action.


Parathyroid Gland Primary Hyperparathyroidism Secondary Hyperparathyroidism Renal Osteodystrophy Serum Calcium Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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