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Vor- und Nachteile der Anwendung von Alfentanil/Sufentanil zur Narkoseeinleitung im Vergleich zu Fentanyl

  • Conference paper
Totale intravenöse Anästhesie (TIVA)

Part of the book series: Klinische Anästhesiologie und Intensivtherapie ((KAI,volume 44))

Zusammenfassung

Bei der Entwicklung synthetischer Opioide für die i.v.-Anästhesie werden folgende Eigenschaften angestrebt:

  1. 1.

    Wirkungsspezifität für die Anästhesiekomponente „Analgesie“ bzw. Suppression der zentralen Verarbeitung und der neuroendokrinen Reaktion auf Schmerzreize,

  2. 2.

    hohe therapeutische Breite,

  3. 3.

    Antagonisierbarkeit,

  4. 4.

    Steuerbarkeit,

  5. 5.

    Fehlen von Kumulation und Toleranz bei Langzeitanwendung, und

  6. 6.

    Fehlen spezifischer und unspezifischer nicht analgetischer Effekte.

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Authors
  1. B. Eberle
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Editors and Affiliations

  1. Klinik für Anästhesiologie, Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, 6500, Mainz, Germany

    W. Dick Univ.-Prof. Dr. Dr. h.c. (Direktor), B. Eberle Dr. , H. Gervais Dr. , W. Heinrichs Priv.-Doz. Dr.  & A. Klein Dr. (Direktor), , ,  & 

  2. Klinik für Anästhesiologie, Klinikum der Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, D-6500, Mainz, Germany

    W. Dick Univ.-Prof. Dr. Dr. h.c. (Direktor) (Direktor)

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© 1993 Springer-Verlag Berlin Heidelberg

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Eberle, B. (1993). Vor- und Nachteile der Anwendung von Alfentanil/Sufentanil zur Narkoseeinleitung im Vergleich zu Fentanyl. In: Dick, W., Eberle, B., Gervais, H., Heinrichs, W., Klein, A. (eds) Totale intravenöse Anästhesie (TIVA). Klinische Anästhesiologie und Intensivtherapie, vol 44. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77966-4_5

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  • DOI: https://doi.org/10.1007/978-3-642-77966-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56248-1

  • Online ISBN: 978-3-642-77966-4

  • eBook Packages: Springer Book Archive

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